Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 3/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9268954 | 0.74 | TDP1 (0.46) | AHR | |
| SCHEMBL25752220 | 0.73 | AHR (0.72) | AHRPTGS1PTGS2ALOX5 | |
| SCHEMBL17147392 | 0.73 | NFE2L2 (0.41) | AHRPTGS1 | |
| SCHEMBL10131350 | 0.72 | CHAT (0.53) | — | |
| SCHEMBL16957748 | 0.72 | AHR (0.34) | AHR | |
| SCHEMBL11788391 | 0.71 | GABBR2 (0.32) | PTGS1PTGS2 | |
| SCHEMBL11788403 | 0.71 | GABBR2 (0.32) | PTGS1PTGS2 | |
| SCHEMBL2011005 | 0.70 | CYP2A6 (0.42) | AHR | |
| SCHEMBL2600068 | 0.70 | AHR (0.48) | AHRPTGS1PTGS2ALOX5 | |
| SCHEMBL16957828 | 0.70 | RAPGEF4 (0.33) | AHRPTGS1PTGS2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021263194-A1 | INHIBITION OF N-GLYCOSYLATED GRP94 | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2021-12-30 | — | — | WO | disclosed |