Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24145389 | 0.90 | LOXL2 (0.35) | LOXL2KDM4ECYP11B2L3MBTL1DGAT2 | |
| SCHEMBL22018101 | 0.87 | CA12 (0.37) | LOXL2KDM4EKMT2A | |
| SCHEMBL22018318 | 0.86 | HPGD (0.40) | KMT2A | |
| SCHEMBL22017892 | 0.84 | CA2 (0.45) | KDM4EKMT2A | |
| SCHEMBL22017885 | 0.84 | CA1 (0.38) | LOXL2KDM4ECYP11B2L3MBTL1DGAT2 | |
| SCHEMBL22017895 | 0.82 | SMN1; SMN2 (0.42) | KDM4EL3MBTL1KMT2A | |
| SCHEMBL22018651 | 0.81 | RORC (0.34) | — | |
| SCHEMBL22018040 | 0.78 | KDM4E (0.48) | KDM4EL3MBTL1KMT2A | |
| SCHEMBL22018290 | 0.75 | CA12 (0.41) | LOXL2KDM4EKMT2A | |
| SCHEMBL24145392 | 0.74 | CA1 (0.37) | KDM4EL3MBTL1KMT2ADGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210403435-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210403435-A1 | HERBICIDAL COMPOUNDS | DDT, CYP4X1, CYP1B1 | LOXL2 1331/4885KDM4E 1729/4885CYP11B2 238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.