Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2410849 | 0.91 | GABRA1 (0.49) | MEN1KMT2AMAPTGABRA1GABRB2 | |
| SCHEMBL2412850 | 0.91 | HPGD (0.53) | RAB9AMAPTGABRA1GABRB2HPGD | |
| SCHEMBL2413110 | 0.89 | GABRA1 (0.47) | GABRA1GABRB2HPGDALDH1A1 | |
| SCHEMBL2410446 | 0.87 | RAB9A (0.51) | RAB9AMEN1KMT2AGABRA1GABRB2 | |
| SCHEMBL2408993 | 0.86 | HPGD (0.53) | MAPTGABRA1GABRB2HPGDALDH1A1 | |
| SCHEMBL2416622 | 0.86 | GABRA1 (0.45) | GABRA1GABRB2HPGDALDH1A1 | |
| SCHEMBL2414418 | 0.85 | HPGD (0.49) | RAB9AGABRA1GABRB2HPGDNPC1 | |
| SCHEMBL2413426 | 0.80 | NPC1 (0.46) | RAB9AGABRA1GABRB2HPGDNPC1 | |
| SCHEMBL2414340 | 0.79 | LPAR1 (0.55) | KMT2AHPGDLMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL2411428 | 0.77 | LPAR1 (0.49) | KMT2AMAPTHPGDLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828107-B1 | HYDROXYBIPHENYL CARBOXYLIC ACIDS AND DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE | SANOFI AVENTIS DEUTSCHLAND (DE) | 2011-09-28 | — | — | EP | disclosed |