Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 2/20 | 0.38 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5315290 | 0.78 | FFAR1 (0.50) | LOXL2IDO1KCNJ1KCNH2CYP2A6 | |
| SCHEMBL23031872 | 0.75 | LOXL2 (0.43) | LOXL2IDO1KCNH2CYP2A6CA12 | |
| SCHEMBL24147174 | 0.74 | LOXL2 (0.45) | LOXL2IDO1KCNJ1KCNH2CYP2A6 | |
| SCHEMBL1004267 | 0.73 | LOXL2 (0.64) | LOXL2IDO1KCNJ1KCNH2CYP2A6 | |
| SCHEMBL7338789 | 0.73 | FFAR1 (0.53) | LOXL2KCNJ1KCNH2CYP2A6FFAR1 | |
| SCHEMBL12500342 | 0.73 | FFAR1 (0.49) | LOXL2IDO1KCNJ1KCNH2CYP2A6 | |
| SCHEMBL13263434 | 0.72 | FFAR1 (0.47) | LOXL2IDO1KCNJ1KCNH2CYP2A6 | |
| SCHEMBL2339110 | 0.72 | CYP2A6 (0.52) | LOXL2IDO1KCNJ1KCNH2CYP2A6 | |
| SCHEMBL1337387 | 0.72 | FFAR1 (0.69) | FFAR1MMP12MMP13 | |
| SCHEMBL27309568 | 0.71 | FFAR1 (0.48) | LOXL2KCNJ1KCNH2CYP2A6FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021263060-A2 | BIFUNCTIONAL BRIDGING COMPOSITIONS FOR VIRAL TRANSDUCTION | LYCIA THERAPEUTICS, INC. (US) | 2021-12-30 | — | — | WO | disclosed |