Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.38 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24146697 | 0.74 | LOXL2 (0.47) | LOXL2CYP2A6TSHRHSD17B10KCNJ1 | |
| SCHEMBL6170108 | 0.70 | LOXL2 (0.52) | LOXL2CYP2A6SAE1UBA2TSHR | |
| SCHEMBL1507376 | 0.67 | ALDH1A1 (0.57) | LOXL2CYP2A6SAE1UBA2TSHR | |
| SCHEMBL5315290 | 0.67 | FFAR1 (0.50) | LOXL2CYP2A6SAE1UBA2KCNJ1 | |
| SCHEMBL1338556 | 0.67 | CYP11B1 (0.60) | LOXL2CYP2A6SAE1UBA2IDO1 | |
| SCHEMBL1004267 | 0.67 | LOXL2 (0.64) | LOXL2CYP2A6SAE1UBA2TSHR | |
| SCHEMBL7338789 | 0.67 | FFAR1 (0.53) | LOXL2CYP2A6SAE1UBA2TSHR | |
| SCHEMBL5193367 | 0.67 | LOXL2 (0.67) | LOXL2CYP2A6SAE1UBA2TSHR | |
| SCHEMBL10355508 | 0.66 | CA2 (0.73) | LOXL2CYP2A6TSHRHSD17B10KCNJ1 | |
| SCHEMBL2339110 | 0.65 | CYP2A6 (0.52) | LOXL2CYP2A6SAE1UBA2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021263060-A2 | BIFUNCTIONAL BRIDGING COMPOSITIONS FOR VIRAL TRANSDUCTION | LYCIA THERAPEUTICS, INC. (US) | 2021-12-30 | — | — | WO | disclosed |