SCHEMBL1004267

SCHEMBL1004267

N#Cc1ccc(CCc2ccc(C#N)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 2/20 0.64
CYP2A6 P11509 2/20 0.64
KCNJ1 P48048 1/20 0.61
KCNH2 Q12809 1/20 0.61
TSHR P16473 2/20 0.55
HSD17B10 Q99714 1/20 0.55
DAO P14920 2/20 0.53
MAOB P27338 4/20 0.52
MAOA P21397 3/20 0.52
CYP19A1 P11511 2/20 0.50
ALDH1A1 P00352 1/20 0.50
CA12 O43570 1/20 0.50
CA2 P00918 1/20 0.50
CA3 P07451 1/20 0.50
CA6 P23280 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
IDO1 P14902 2/20 0.48
MMP12 P39900 1/20 0.46
MMP13 P45452 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10452241 0.92 LOXL2 (0.56) LOXL2CYP2A6KCNJ1KCNH2TSHR
SCHEMBL6960019 0.90 MAOB (0.66) LOXL2CYP2A6KCNJ1KCNH2TSHR
SCHEMBL9640908 0.89 TSHR (0.62) LOXL2CYP2A6KCNJ1KCNH2TSHR
SCHEMBL10569888 0.89 TSHR (0.68) LOXL2CYP2A6KCNJ1KCNH2TSHR
SCHEMBL8094406 0.88 LOXL2 (0.52) LOXL2CYP2A6KCNJ1KCNH2TSHR
SCHEMBL7666462 0.88 CYP2A6 (0.86) LOXL2CYP2A6KCNJ1KCNH2TSHR
SCHEMBL10355508 0.88 CA2 (0.73) LOXL2CYP2A6KCNJ1KCNH2TSHR
SCHEMBL9552723 0.88 LOXL2 (0.52) LOXL2CYP2A6KCNJ1KCNH2TSHR
SCHEMBL16582463 0.87 TSHR (0.71) LOXL2CYP2A6KCNJ1KCNH2TSHR
SCHEMBL16582531 0.87 TSHR (0.71) LOXL2CYP2A6KCNJ1KCNH2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140349120-A1 Epoxy Resin Composition and High Frequency Circuit Board Manufactured by Using the Same SHENGYI TECHNOLOGY CO., LTD. (CN) 2014-11-27 US claimed
US-3984452-A Process for the preparation of a p,p'-dicyanobibenzyl and a m,m'-dicyanobibenzyl AKZONA INCORPORATED (US) 1976-10-05 US claimed
CN-116178678-A Bridged electron donor-acceptor polymer and preparation method and application thereof 中山大学 2023-05-30 CN disclosed
US-20230120881-A1 BINUCLEAR GOLD(I) COMPOUNDS FOR PHOTOCATALYSIS APPLICATIONS University of Hong Kong Versitech Limited (CN) 2023-04-20 US disclosed
EP-4122940-A1 BINUCLEAR GOLD(I) COMPOUNDS FOR PHOTOCATALYSIS APPLICATIONS Versitech Limited (CN) 2023-01-25 EP disclosed
CN-113264849-A Stilbene solid fluorescent material 青岛科技大学 2021-08-17 CN disclosed
US-11081367-B2 Support and method for producing semiconductor device-mounting substrate using the same MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2021-08-03 US disclosed
EP-3618587-A1 SUPPORT AND METHOD FOR MANUFACTURING SEMICONDUCTOR ELEMENT MOUNTING SUBSTRATE IN WHICH SAID SUPPORT IS USED Mitsubishi Gas Chemical Company, Inc. (JP) 2020-03-04 EP disclosed
US-20200043752-A1 SUPPORT AND METHOD FOR PRODUCING SEMICONDUCTOR DEVICE-MOUNTING SUBSTRATE USING THE SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2020-02-06 US disclosed
EP-3184171-B1 PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS CHEVRON PHILLIPS CHEMICAL CO LP (US) 2019-03-20 EP disclosed
US-10144752-B2 Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2018-12-04 US disclosed
US-6326395-B1 AMIDINE OR AMIDE SUBSTITUTED FURAN DERIVATIVES DUKE UNIVERSITY 2001-12-04 US disclosed
US-5656401-A Electroluminescent device comprising oxadiazole compounds luminescent material, oxadiazole compounds for the device, and method of producing oxadiazole compounds RICOH COMPANY, LTD. (JP) 1997-08-12 US disclosed
US-5610309-A Electroluminescent device comprising oxadiazole compounds luminescent material, oxadiazole compounds for the device, and method of producing oxadiazole compounds RICOH COMPANY, LTD. (JP) 1997-03-11 US disclosed
US-5597925-A CYCLIZATION RICOH COMPANY, LTD. (JP) 1997-01-28 US disclosed
US-5420288-A Electron transporting material, planar displays RICOH COMPANY, LTD. (JP) 1995-05-30 US disclosed
US-4571443-A Process for effecting oxidative dehydrodimerization THE STANDARD OIL COMPANY (US) 1986-02-18 US disclosed
US-3984452-A Process for the preparation of a p,p'-dicyanobibenzyl and a m,m'-dicyanobibenzyl AKZONA INCORPORATED (US) 1976-10-05 US disclosed
US-3984452-A Process for the preparation of a p,p'-dicyanobibenzyl and a m,m'-dicyanobibenzyl AKZONA INCORPORATED (US) 1976-10-05 US disclosed
US-3984452-A Process for the preparation of a p,p'-dicyanobibenzyl and a m,m'-dicyanobibenzyl AKZONA INCORPORATED (US) 1976-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10144752-B2 Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins NIT2, NCLN, NPM1 LOXL2 3624/4885CYP2A6 4835/4885KCNJ1 2512/4885
US-20230120881-A1 BINUCLEAR GOLD(I) COMPOUNDS FOR PHOTOCATALYSIS APPLICATIONS PPOX, AP3M1, AP2M1 LOXL2 2961/4885CYP2A6 1360/4885KCNJ1 1630/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.