SCHEMBL24147199

SCHEMBL24147199

N#CCc1c(C#N)nc(C#N)nc1C#N

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.32
MAPT P10636 1/20 0.32
KDM4E B2RXH2 3/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
MAPK1 P28482 2/20 0.30
F2 P00734 1/20 0.30
LMNA P02545 1/20 0.30
HTT P42858 1/20 0.30
NPC1 O15118 1/20 0.30
GALR3 O60755 1/20 0.30
ALDH1A1 P00352 1/20 0.30
TP53 P04637 1/20 0.30
RAB9A P51151 1/20 0.30
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24147202 0.86
SCHEMBL24147217 0.81 CTSK (0.31)
SCHEMBL24147201 0.74 TSHR (0.33) TSHRTDP1SMN1; SMN2MAPTKDM4E
SCHEMBL24147213 0.74
SCHEMBL24108204 0.70 TSHR (0.37) TSHRTDP1SMN1; SMN2MAPTMAPK1
SCHEMBL24147287 0.70 CTSK (0.33) TSHRTDP1
SCHEMBL24146455 0.70 MEN1 (0.33) TSHRMAPTKDM4EMEN1KMT2A
SCHEMBL9735359 0.69 MAPK1 (0.34) TSHRTDP1SMN1; SMN2MAPTKDM4E
SCHEMBL24147200 0.69 KDM4E (0.33) TSHRMAPTKDM4EMEN1KMT2A
SCHEMBL24108407 0.69 CYP11B1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230247901-A1 Organic Electronic Device Comprising a Compound of Formula (I), Display Device Comprising the Organic Electronic Device as Well as Compounds of Formula (I) for Use in Organic Electronic Devices NOVALED GMBH (DE) 2023-08-03 US disclosed
WO-2023275021-A1 ORGANIC COMPOUND OF FORMULA (I) FOR USE IN ORGANIC ELECTRONIC DEVICES, AN ORGANIC ELECTRONIC DEVICE COMPRISING A COMPOUND OF FORMULA (I) AND A DISPLAY DEVICE COMPRISING THE ORGANIC ELECTRONIC DEVICE NOVALED GMBH (DE) 2023-01-05 WO disclosed
EP-4113639-A1 ORGANIC COMPOUND OF FORMULA (I) FOR USE IN ORGANIC ELECTRONIC DEVICES, AN ORGANIC ELECTRONIC DEVICE COMPRISING A COMPOUND OF FORMULA (I) AND A DISPLAY DEVICE COMPRISING THE ORGANIC ELECTRONIC DEVICE Novaled GmbH (DE) 2023-01-04 EP disclosed
WO-2022263531-A1 ACTIVE-MATRIX OLED DISPLAY NOVALED GMBH (DE) 2022-12-22 WO disclosed
EP-4106027-A1 ACTIVE-MATRIX OLED DISPLAY Novaled GmbH (DE) 2022-12-21 EP disclosed
EP-3989305-A1 ORGANIC ELECTRONIC DEVICE COMPRISING A COMPOUND OF FORMULA (1), DISPLAY DEVICE COMPRISING THE ORGANIC ELECTRONIC DEVICE AS WELL AS COMPOUNDS OF FORMULA (1) FOR USE IN ORGANIC ELECTRONIC DEVICES Novaled GmbH (DE) 2022-04-27 EP disclosed
WO-2021259784-A2 ORGANIC ELECTRONIC DEVICE COMPRISING A COMPOUND OF FORMULA (I), DISPLAY DEVICE COMPRISING THE ORGANIC ELECTRONIC DEVICE AS WELL AS COMPOUNDS OF FORMULA (I) FOR USE IN ORGANIC ELECTRONIC DEVICES NOVALED GMBH (DE) 2021-12-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230247901-A1 Organic Electronic Device Comprising a Compound of Formula (I), Display Device Comprising the Organic Electronic Device as Well as Compounds of Formula (I) for Use in Organic Electronic Devices AOX1, CYP2C19, CYP2C9 TSHR 4329/4885TDP1 2861/4885SMN1; SMN2 3520/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.