Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6240962 | 0.75 | ALDH1A1 (0.33) | MAPK1SMN1; SMN2ALDH1A1TP53MAPT | |
| SCHEMBL9617370 | 0.74 | KDM4E (0.43) | MAPK1SMN1; SMN2ALDH1A1TSHRTDP1 | |
| SCHEMBL1993425 | 0.73 | MAPK1 (0.43) | MAPK1SMN1; SMN2ALDH1A1TSHRTDP1 | |
| SCHEMBL8418395 | 0.73 | ALDH1A1 (0.32) | MAPK1SMN1; SMN2ALDH1A1TP53MAPT | |
| SCHEMBL15727043 | 0.73 | ALDH1A1 (0.32) | MAPK1SMN1; SMN2ALDH1A1TP53MAPT | |
| SCHEMBL10325214 | 0.72 | MAPK1 (0.32) | MAPK1SMN1; SMN2ALDH1A1TSHRTDP1 | |
| SCHEMBL21927620 | 0.71 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1TSHRHTTKDM4E | |
| SCHEMBL10820320 | 0.70 | MAPK1 (0.31) | MAPK1SMN1; SMN2ALDH1A1TSHRTDP1 | |
| SCHEMBL24147199 | 0.69 | TSHR (0.34) | MAPK1SMN1; SMN2ALDH1A1TSHRTDP1 | |
| SCHEMBL11878461 | 0.69 | CTSK (0.34) | MAPK1SMN1; SMN2ALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5138056-A | POLYCYANOPYRIMIDINES AND PROCESS FOR THEIR PREPARATION | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-11 | — | — | US | disclosed |
| EP-0462452-A1 | Polycyanopyrimidines and process for their preparation | BAYER AG (DE) | 1991-12-27 | — | — | EP | disclosed |