Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 7/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24693229 | 0.77 | HRH4 (0.34) | CACNA2D1HRH4HRH3 | |
| SCHEMBL8262509 | 0.77 | PHGDH (0.34) | HRH3 | |
| SCHEMBL12568608 | 0.76 | HRH4 (0.36) | HRH4HRH3 | |
| SCHEMBL10197112 | 0.76 | HRH4 (0.36) | HRH4HRH3 | |
| SCHEMBL20247967 | 0.75 | SHBG (0.35) | HRH3 | |
| SCHEMBL13638195 | 0.75 | GNAI3 (0.41) | HRH3 | |
| SCHEMBL21214494 | 0.73 | HRH3 (0.39) | CACNA2D1HRH4HRH3 | |
| SCHEMBL21613836 | 0.73 | HRH3 (0.32) | HRH3 | |
| SCHEMBL25448085 | 0.72 | HRH3 (0.35) | HRH3 | |
| SCHEMBL26530253 | 0.72 | HRH3 (0.39) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021262541-A1 | COMPANION DIAGNOSTIC TOOL FOR MUTANT P53 REACTIVATING COMPOUNDS | PMV PHARMACEUTICALS, INC. (US) | 2021-12-30 | — | — | WO | disclosed |