Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INPPL1 | O15357 | 1/20 | 0.50 |
| ▸ | GLP1R | P43220 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 6/20 | 0.45 |
| ▸ | BCL6 | P41182 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL30662706 | 0.91 | GLP1R (0.48) | INPPL1GLP1RHTR2CBCL6ALDH1A1 | |
| SCHEMBL24320574 | 0.89 | GLP1R (0.47) | INPPL1GLP1RCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL26914340 | 0.86 | GLP1R (0.44) | INPPL1GLP1RBCL6ROCK2MAPK14 | |
| SCHEMBL26914337 | 0.86 | GLP1R (0.44) | INPPL1GLP1RBCL6ROCK2MAPK14 | |
| SCHEMBL24485507 | 0.85 | GPR119 (0.43) | INPPL1GLP1RHTR2CBCL6ROCK2 | |
| SCHEMBL30149315 | 0.85 | GPR119 (0.43) | INPPL1GLP1RHTR2CBCL6ROCK2 | |
| Hydrochloric Acid SCHEMBL30662717 | 0.85 | GLP1R (0.44) | INPPL1GLP1RBCL6ROCK2MAPK14 | |
| Hydrochloric Acid SCHEMBL26914560 | 0.85 | GLP1R (0.44) | INPPL1GLP1RBCL6ROCK2MAPK14 | |
| SCHEMBL20288052 | 0.84 | HTR3A (0.51) | INPPL1GLP1RHTR2CHTR1ASLC6A2 | |
| SCHEMBL24147365 | 0.83 | INPPL1 (0.41) | INPPL1GLP1RHTR2CHTR1ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230391760-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. | 2023-12-07 | — | — | US | disclosed |
| WO-2021259309-A1 | GLP-1 RECEPTOR AGONIST, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 广州市恒诺康医药科技有限公司 | 2021-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230391760-A1 | HETEROCYCLIC GLP-1 AGONISTS | GLP1R, GIPR, GCGR | INPPL1 2113/4885GLP1R 1/4885HTR2C 160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.