Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.47 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2364077 | 0.80 | TSHR (0.52) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL10952688 | 0.78 | TSHR (0.68) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL167051 | 0.78 | TSHR (0.68) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL35714 | 0.77 | TSHR (0.54) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL22675564 | 0.77 | TSHR (0.54) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Water SCHEMBL28173091 | 0.76 | TSHR (0.65) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL257206 | 0.76 | TSHR (0.52) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL2059656 | 0.76 | ZDHHC20 (0.53) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL29055456 | 0.74 | TSHR (0.50) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL10821153 | 0.74 | TSHR (0.50) | TSHRALDH1A1MAPK1TDP1ZDHHC20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021262596-A1 | METHODS AND COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION | PMV PHARMACEUTICALS, INC. (US) | 2021-12-30 | — | — | WO | disclosed |