SCHEMBL2364077

SCHEMBL2364077

C=CC(=O)NCCC(N)=O

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.52
ALDH1A1 P00352 3/20 0.52
MAPK1 P28482 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
ZDHHC20 Q5W0Z9 1/20 0.48
ZDHHC2 Q9UIJ5 1/20 0.48
FGFR4 P22455 1/20 0.38
TGM2 P21980 5/20 0.36
GAA P10253 1/20 0.35
MAPT P10636 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
BTK Q06187 3/20 0.31
ECE1 P42892 1/20 0.31
LMNA P02545 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28344839 0.89 ZDHHC20 (0.57) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL20179467 0.85 ZDHHC20 (0.63) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL5968142 0.85 ZDHHC20 (0.63) TSHRALDH1A1MAPK1TDP1ZDHHC20
Acrylamide SCHEMBL7163814 0.81 TSHR (0.56) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL22721386 0.81 TSHR (0.46) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL24150482 0.80 TSHR (0.50) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL167051 0.80 TSHR (0.68) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL10952688 0.80 TSHR (0.68) TSHRALDH1A1MAPK1TDP1ZDHHC20
Urea SCHEMBL29002144 0.79 ZDHHC20 (0.47) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL3897974 0.79 MAPT (0.32) MAPTECE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3732259-B1 A COMPOSITION TO PRODUCE SUPPORT SUB-STRUCTURES FOR 3D PHOTOPOLYMER JETTING BASF SE (DE) 2022-11-30 EP claimed
US-11325315-B2 Composition to produce support sub-structures for 3D photopolymer jetting BASF SE (DE) 2022-05-10 US claimed
US-11325315-B2 Composition to produce support sub-structures for 3D photopolymer jetting BASF SE (DE) 2022-05-10 US disclosed
US-7989411-B2 Composition which contains a mixture of mono-, di and triglycerides and glycerine KAO CORPORATION, S.A. (ES) 2011-08-02 US disclosed
US-RE41585-E1 Method for controlling the rheology of an aqueous fluid and gelling agent therefor AKZO NOBEL NV 2010-08-24 US disclosed
US-20100035781-A1 Composition which Contains a Mixture of Mono-, Di and Triglycerides and Glycerine KAO CORPORATION, S.A. (ES) 2010-02-11 US disclosed
EP-2029711-B1 COMPOSITION WHICH CONTAINS A MIXTURE OF MONO-, DI-, AND TRIGLYCERIDES AND GLYCERINE KAO CORP SA (ES) 2010-02-10 EP disclosed
EP-1292651-B1 VISCOELASTIC SURFACTANTS AND COMPOSITIONS CONTAINING SAME AKZO NOBEL NV (NL) 2010-01-06 EP disclosed
EP-2029711-A1 COMPOSITION WHICH CONTAINS A MIXTURE OF MONO-, DI-, AND TRIGLYCERIDES AND GLYCERINE KAO CORPORATION, S.A. (ES) 2009-03-04 EP disclosed
WO-2007141066-A1 COMPOSITION WHICH CONTAINS A MIXTURE OF MONO-, DI-, AND TRIGLYCERIDES AND GLYCERINE KAO CORPORATION, S.A. (ES) 2007-12-13 WO disclosed
US-7060661-B2 Aqueous, acidic compositions thickened with an amidoamine oxide gelling agent AKZO NOBEL N.V. (NL) 2006-06-13 US disclosed
US-6506710-B1 Gelling agent composition which comprises at least one glycol as a solvent, and at least one amidoamine oxide gelling agent AKZO NOBEL N.V. (NL) 2003-01-14 US disclosed
EP-1042425-B1 A METHOD FOR CONTROLLING THE RHEOLOGY OF AN AQUEOUS FLUID AND GELLING AGENT THEREFOR AKZO NOBEL NV (NL) 2002-11-06 EP disclosed
US-20020147114-A1 Acid thickeners and uses thereof NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2002-10-10 US disclosed
WO-2001081499-A2 VISCOELASTIC SURFACTANTS AND COMPOSITIONS CONTAINING SAME AKZO NOBEL N.V. (NL) 2001-11-01 WO disclosed
US-6265373-B1 WEIGHT RATIO OF TRIGLYCERIDE/DIGLYCERIDE/MONOGLYCERIDE BEING 46 TO 90/9 TO 35/1 TO 15. KAO CORPORATION S.A. (ES) 2001-07-24 US disclosed
US-6239183-B1 INJECTING VISCOELASTIC FLUID CONTAINING AMIDOAMINE OXIDE GELLING AGENT AND QUATERNARY AMMONIUM SALT OF AROMATIC DICARBOXYLIC ACID INTO SUBTERRANEAN FORMATION AKZO NOBEL NV (NL) 2001-05-29 US disclosed
EP-1045021-A1 Composition comprising a mixture of alkoxylated mono-, di- and triglycerides and glycerine KAO CORPORATION, S.A. (ES) 2000-10-18 EP disclosed
EP-1042425-A1 A METHOD FOR CONTROLLING THE RHEOLOGY OF AN AQUEOUS FLUID AND GELLING AGENT THEREFOR Akzo Nobel N.V. (NL) 2000-10-11 EP disclosed
WO-1999032572-A1 A METHOD FOR CONTROLLING THE RHEOLOGY OF AN AQUEOUS FLUID AND GELLING AGENT THEREFOR AKZO NOBEL N.V. (NL) 1999-07-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100035781-A1 Composition which Contains a Mixture of Mono-, Di and Triglycerides and Glycerine MGLL, ABHD6, LIPC TSHR 2522/4885ALDH1A1 1601/4885MAPK1 3612/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.