Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | PRNP | P04156 | 1/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 4/20 | 0.32 |
| ▸ | SCN1B | Q07699 | 2/20 | 0.32 |
| ▸ | SCN1A | P35498 | 3/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24151588 | 0.93 | TRPA1 (0.43) | TRPA1CASP3PRNPSCN8ASCN1B | |
| SCHEMBL24152377 | 0.90 | TRPA1 (0.48) | TRPA1CASP3PRNPSCN8ASCN1B | |
| SCHEMBL24151575 | 0.88 | TRPA1 (0.61) | TRPA1CASP3 | |
| SCHEMBL24152360 | 0.87 | TRPA1 (0.43) | TRPA1CASP3PRNP | |
| SCHEMBL24151578 | 0.87 | TRPA1 (0.46) | TRPA1CASP3PRNPSCN8ASCN1B | |
| SCHEMBL24151584 | 0.85 | TRPA1 (0.42) | TRPA1CASP3PRNPSCN8ASCN1B | |
| SCHEMBL24151586 | 0.84 | TRPA1 (0.47) | TRPA1PRNP | |
| SCHEMBL24151589 | 0.84 | TRPA1 (0.47) | TRPA1CASP3PRNPSCN8ASCN1B | |
| SCHEMBL24152375 | 0.84 | TRPA1 (0.41) | TRPA1PRNPSCN8ASCN1BSCN1A | |
| SCHEMBL24152363 | 0.83 | TRPA1 (0.43) | TRPA1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021260722-A1 | DESIGN, SYNTHESIS OF NOVEL OXYINDOLE INHIBITORS OF DENV RNA DEPENDENT RNA POLYMERASE | TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) | 2021-12-30 | — | — | WO | disclosed |