Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 10/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | SCN1B | Q07699 | 3/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.33 |
| ▸ | SCN1A | P35498 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24151575 | 0.92 | TRPA1 (0.61) | TRPA1ALDH1A1MAPTCASP3 | |
| SCHEMBL24152517 | 0.91 | TRPA1 (0.48) | TRPA1ALDH1A1HSD17B10MAPTPKM | |
| SCHEMBL24151578 | 0.90 | TRPA1 (0.46) | TRPA1SCN1BSCN8ASCN1ASCN5A | |
| SCHEMBL24151573 | 0.90 | TRPA1 (0.45) | TRPA1SCN1BSCN8ASCN1ASCN5A | |
| SCHEMBL24151584 | 0.89 | TRPA1 (0.42) | TRPA1ALDH1A1MAPTTDP1MAPK1 | |
| SCHEMBL24151588 | 0.88 | TRPA1 (0.43) | TRPA1SCN1BSCN8ASCN1ASCN5A | |
| SCHEMBL24151589 | 0.88 | TRPA1 (0.47) | TRPA1MAPTSCN1BSCN8APRNP | |
| SCHEMBL24151586 | 0.88 | TRPA1 (0.47) | TRPA1MAPTPRNP | |
| SCHEMBL24152375 | 0.87 | TRPA1 (0.41) | TRPA1ALDH1A1MAPTTDP1HSP90AA1 | |
| SCHEMBL24153263 | 0.81 | TRPA1 (0.38) | TRPA1MAPTPKMPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021260722-A1 | DESIGN, SYNTHESIS OF NOVEL OXYINDOLE INHIBITORS OF DENV RNA DEPENDENT RNA POLYMERASE | TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) | 2021-12-30 | — | — | WO | disclosed |