Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.31 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 2/20 | 0.30 |
| ▸ | CASP7 | P55210 | 2/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP6 | P55212 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SNCA | P37840 | 1/20 | 0.30 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.30 |
| ▸ | PRNP | P04156 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24151575 | 0.89 | TRPA1 (0.61) | TRPA1CA12CA1CA2CA9 | |
| SCHEMBL24152377 | 0.88 | TRPA1 (0.48) | TRPA1SCN1BSCN8ACASP3MAPT | |
| SCHEMBL24151586 | 0.85 | TRPA1 (0.47) | TRPA1CA12CA1CA2CA9 | |
| SCHEMBL24151578 | 0.85 | TRPA1 (0.46) | TRPA1SCN1BSCN8ACASP3PRNP | |
| SCHEMBL24151573 | 0.84 | TRPA1 (0.45) | TRPA1SCN1BSCN8ACASP3PRNP | |
| SCHEMBL24151588 | 0.84 | TRPA1 (0.43) | TRPA1SCN1BSCN8ACASP3PRNP | |
| SCHEMBL24151584 | 0.83 | TRPA1 (0.42) | TRPA1SCN1BSCN8ACASP3CASP7 | |
| SCHEMBL24152830 | 0.82 | TRPA1 (0.38) | TRPA1SCN1BSCN8ACASP3CASP7 | |
| SCHEMBL24152375 | 0.82 | TRPA1 (0.41) | TRPA1SCN1BSCN8AMAPTPRNP | |
| SCHEMBL24152362 | 0.80 | TRPA1 (0.53) | TRPA1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021260722-A1 | DESIGN, SYNTHESIS OF NOVEL OXYINDOLE INHIBITORS OF DENV RNA DEPENDENT RNA POLYMERASE | TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) | 2021-12-30 | — | — | WO | disclosed |