Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CDC25A | P30304 | 9/20 | 0.33 |
| ▸ | CASP3 | P42574 | 5/20 | 0.33 |
| ▸ | CASP7 | P55210 | 4/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.32 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24153255 | 0.92 | TRPA1 (0.40) | TRPA1MAPTCASP3CASP7RXFP1 | |
| SCHEMBL24152382 | 0.87 | TRPA1 (0.44) | TRPA1MAPTALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL24152517 | 0.86 | TRPA1 (0.48) | TRPA1MAPTALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL24151587 | 0.84 | TRPA1 (0.42) | TRPA1MAPTCASP3CASP7ALDH1A1 | |
| SCHEMBL24152377 | 0.82 | TRPA1 (0.48) | TRPA1MAPTCASP3ALDH1A1KMT2A | |
| SCHEMBL24153269 | 0.82 | TRPA1 (0.40) | TRPA1MAPTCASP3CASP7KMT2A | |
| SCHEMBL24152372 | 0.82 | TRPA1 (0.47) | TRPA1MAPTCASP3CASP7ALDH1A1 | |
| SCHEMBL24152359 | 0.81 | TRPA1 (0.50) | TRPA1CASP3CASP7 | |
| SCHEMBL24152464 | 0.81 | TRPA1 (0.41) | TRPA1MAPTCASP3CASP7ALDH1A1 | |
| SCHEMBL24152462 | 0.81 | TRPA1 (0.41) | TRPA1MAPTCASP3CASP7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021260722-A1 | DESIGN, SYNTHESIS OF NOVEL OXYINDOLE INHIBITORS OF DENV RNA DEPENDENT RNA POLYMERASE | TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) | 2021-12-30 | — | — | WO | disclosed |