Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.36 |
| ▸ | MAPT | P10636 | 9/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SCN1B | Q07699 | 4/20 | 0.32 |
| ▸ | SCN8A | Q9UQD0 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24152377 | 0.91 | TRPA1 (0.48) | TRPA1ALDH1A1MAPTPKMTDP1 | |
| SCHEMBL24151587 | 0.91 | TRPA1 (0.42) | TRPA1ALDH1A1MAPTTDP1SMN1; SMN2 | |
| SCHEMBL24152368 | 0.86 | TRPA1 (0.45) | TRPA1ALDH1A1MAPTKMT2AL3MBTL1 | |
| SCHEMBL24152372 | 0.85 | TRPA1 (0.47) | TRPA1ALDH1A1MAPTPKMTDP1 | |
| SCHEMBL24152359 | 0.85 | TRPA1 (0.50) | TRPA1MAPK1 | |
| SCHEMBL24152382 | 0.84 | TRPA1 (0.44) | TRPA1ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL24152529 | 0.84 | TRPA1 (0.45) | TRPA1 | |
| SCHEMBL24151575 | 0.83 | TRPA1 (0.61) | TRPA1ALDH1A1MAPT | |
| SCHEMBL24152464 | 0.83 | TRPA1 (0.41) | TRPA1ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL24152462 | 0.83 | TRPA1 (0.41) | TRPA1MAPTSMN1; SMN2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021260722-A1 | DESIGN, SYNTHESIS OF NOVEL OXYINDOLE INHIBITORS OF DENV RNA DEPENDENT RNA POLYMERASE | TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) | 2021-12-30 | — | — | WO | disclosed |