SCHEMBL241542

SCHEMBL241542

c1ccc2cc3c(ccc4ccnnc43)cc2c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.40
HIF1A Q16665 3/20 0.40
HSD17B10 Q99714 3/20 0.40
CYP1B1 Q16678 1/20 0.40
KDM4E B2RXH2 5/20 0.35
MAPT P10636 3/20 0.35
CYP3A4 P08684 2/20 0.35
ALOX15 P16050 2/20 0.35
HTT P42858 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
LMNA P02545 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
GMNN O75496 1/20 0.35
TP53 P04637 1/20 0.35
HSP90AA1 P07900 1/20 0.35
MMP2 P08253 1/20 0.35
CYP2D6 P10635 1/20 0.35
MMP9 P14780 1/20 0.35
TSHR P16473 1/20 0.35
NFKB1 P19838 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29456717 1.00 ALDH1A1 (0.40) ALDH1A1HIF1AHSD17B10CYP1B1KDM4E
SCHEMBL26644609 0.85 ALDH1A1 (0.32) ALDH1A1HIF1AHSD17B10CYP1B1KDM4E
SCHEMBL474149 0.82 ALDH1A1 (0.46) ALDH1A1HIF1AHSD17B10CYP1B1KDM4E
SCHEMBL5083299 0.81 ALDH1A1 (0.45) ALDH1A1HIF1AHSD17B10CYP1B1KDM4E
SCHEMBL30678718 0.79 ALDH1A1 (0.46) ALDH1A1HSD17B10KDM4EMAPTCYP3A4
SCHEMBL31389329 0.78 ALDH1A1 (0.47) ALDH1A1HIF1AHSD17B10CYP1B1KDM4E
SCHEMBL31619715 0.77 ALDH1A1 (0.45) ALDH1A1HIF1AHSD17B10CYP1B1KDM4E
SCHEMBL4651081 0.77 ALDH1A1 (0.45) ALDH1A1HIF1AHSD17B10CYP1B1KDM4E
SCHEMBL30132322 0.76 CCR1 (0.60) ALDH1A1HIF1AHSD17B10CYP1B1KDM4E
SCHEMBL5821259 0.76 CCR1 (0.60) ALDH1A1HIF1AHSD17B10CYP1B1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 622 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8076072-B2 Nucleic acid labeling compounds AFFYMETRIX, INC. (US) 2011-12-13 US claimed
US-8026057-B2 Nucleic acid labeling compounds AFFYMETRIX, INC. (US) 2011-09-27 US claimed
US-7468243-B2 Nucleotide sequence labelling compoumd four use as tool in genetic engineering AFFYMETRIX, INC. (US) 2008-12-23 US claimed
US-7291463-B2 Incubating/condensating pseudoisocytidine molecule with (1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride to provide a pseudouridine molecule; oncology diagnosis AFFYMETRIX, INC. (US) 2007-11-06 US claimed
US-7282327-B2 Nucleic acid labeling compounds AFFYMETRIX, INC. (US) 2007-10-16 US claimed
US-20260035749-A1 METHODS AND COMPOSITIONS FOR PREDICTING AND/OR MONITORING CARDIOVASCULAR DISEASE AND TREATMENTS THEREFOR CARDIO DIAGNOSTICS INC (US) 2026-02-05 US disclosed
US-12297221-B2 Functionalization and purification of molecules by reversible group exchange ILLUMINA, INC. (US) 2025-05-13 US disclosed
US-20240384262-A1 LINKING SEQUENCE READS USING PAIRED CODE TAGS ILLUMINA, INC. 2024-11-21 US disclosed
US-20240360513-A1 COMPOSITIONS AND METHODS FOR DETECTING PREDISPOSITION TO CARDIOVASCULAR DISEASE UNIV IOWA RES FOUND (US) 2024-10-31 US disclosed
US-20240327916-A1 METHODS AND COMPOSITIONS FOR PREDICTING AND/OR MONITORING CARDIOVASCULAR DISEASE AND INTERVENTIONS THEREFOR Cardio Diagnostics, Inc. 2024-10-03 US disclosed
US-12043869-B2 Compositions and methods for detecting predisposition to cardiovascular disease UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2024-07-23 US disclosed
US-11993772-B2 Linking sequence reads using paired code tags ILLUMINA, INC. (US) 2024-05-28 US disclosed
US-4272506-A BINDING A LABELED MEMBER OF A SPECIFIC BINDING PAIR TO A MERCAPTO-ACTIVATED SUPPORT THROUGH CLEAVABLE DISULFIDE LINKAGES; IMMUNOASSAY; ACCURACY SYVA COMPANY (US) 1981-06-09 US disclosed
US-4256834-A REPRESSING THE SIGNALS PRODUCED BY UNBOUND LABELS; SENSITIVITY SYVA COMPANY (US) 1981-03-17 US disclosed
EP-0022768-A1 MACROMOLECULAR ENVIRONMENT CONTROL IN SPECIFIC RECEPTOR ASSAYS. SYVA CO (US) 1981-01-28 EP disclosed
EP-0017908-A1 A method for determining the presence in a sample of an analyte and a kit for use in this method SYVA COMPANY (US) 1980-10-29 EP disclosed
EP-0015695-A1 Support-ligand analog-fluorescer conjugate and serum assay method involving such conjugate SYVA COMPANY (US) 1980-09-17 EP disclosed
EP-0022768-A4 MACROMOLECULAR ENVIRONMENT CONTROL IN SPECIFIC RECEPTOR ASSAYS. SYVA CO (US) 1980-08-18 EP disclosed
US-4193983-A Labeled liposome particle compositions and immunoassays therewith SYVA COMPANY (US) 1980-03-18 US disclosed
WO-1979000882-A1 MACROMOLECULAR ENVIRONMENT CONTROL IN SPECIFIC RECEPTOR ASSAYS SYVA CO (US) 1979-11-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035749-A1 METHODS AND COMPOSITIONS FOR PREDICTING AND/OR MONITORING CARDIOVASCULAR DISEASE AND TREATMENTS THEREFOR DNMT3A, MECP2, DNMT3L ALDH1A1 1098/4885HIF1A 1826/4885HSD17B10 1383/4885
US-12297221-B2 Functionalization and purification of molecules by reversible group exchange PHAX, ALKBH1, JMJD6 ALDH1A1 4037/4885HIF1A 4465/4885HSD17B10 4845/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.