Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1094981 | 0.86 | ALDH1A1 (0.50) | ALDH1A1HSD17B10HIF1AHPGDGLA | |
| SCHEMBL29994991 | 0.86 | ALDH1A1 (0.50) | ALDH1A1HSD17B10HIF1AHPGDGLA | |
| SCHEMBL31619715 | 0.85 | ALDH1A1 (0.45) | ALDH1A1HSD17B10HIF1ACYP1B1HPGD | |
| SCHEMBL4651081 | 0.85 | ALDH1A1 (0.45) | ALDH1A1HSD17B10HIF1ACYP1B1HPGD | |
| SCHEMBL15124859 | 0.84 | ALDH1A1 (0.48) | ALDH1A1HSD17B10HIF1AHPGDGLA | |
| SCHEMBL15124134 | 0.84 | ALDH1A1 (0.48) | ALDH1A1HSD17B10HIF1AHPGDGLA | |
| SCHEMBL241542 | 0.81 | ALDH1A1 (0.40) | ALDH1A1HSD17B10HIF1ACYP1B1HPGD | |
| SCHEMBL29456717 | 0.81 | ALDH1A1 (0.40) | ALDH1A1HSD17B10HIF1ACYP1B1HPGD | |
| Cinnoline SCHEMBL29367576 | 0.77 | ALDH1A1 (0.50) | ALDH1A1HSD17B10HPGDGLAMAPT | |
| Cinnoline SCHEMBL8197 | 0.77 | ALDH1A1 (0.50) | ALDH1A1HSD17B10HPGDGLAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1909958-A2 | METAL-ORGANIC FRAMEWORK CATALYSTS AND THEIR USE IN HYDROCARBON TRANSFORMATION | Universitetet I Oslo (NO) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007007113-A2 | METAL-ORGANIC FRAMEWORK CATALYSTS AND THEIR USE IN HYDROCARBON TRANSFORMATION | UNIVERSITETET I OSLO (NO) | 2007-01-18 | — | — | WO | disclosed |