Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 3/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.47 |
| ▸ | ACMSD | Q8TDX5 | 5/20 | 0.45 |
| ▸ | DHFR | P00374 | 2/20 | 0.45 |
| ▸ | HNF4A | P41235 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2414649 | 0.91 | STAT3 (0.58) | STAT3MCL1ACMSDDHFRHNF4A | |
| SCHEMBL2412122 | 0.89 | MCL1 (0.59) | STAT3MCL1ACMSDDHFRHNF4A | |
| SCHEMBL2415460 | 0.84 | ROCK1 (0.42) | STAT3KDM4ELMNAHSD17B10MCHR1 | |
| SCHEMBL2415565 | 0.83 | STAT3 (0.51) | STAT3MCL1ACMSDDHFRHNF4A | |
| SCHEMBL14015153 | 0.82 | GABRA1 (0.49) | PPARASTING1USP2ALDH1A1HPGD | |
| SCHEMBL2411426 | 0.80 | LPAR1 (0.56) | STAT3PPARASTING1KDM4ELMNA | |
| SCHEMBL330405 | 0.77 | ACMSD (0.72) | PPARASTING1MCL1ACMSDDHFR | |
| SCHEMBL12655702 | 0.76 | KAT8 (0.55) | STAT3PPARASTING1MCL1HPGD | |
| SCHEMBL2414719 | 0.76 | SNCA (0.51) | PPARASTING1MCL1ACMSDDHFR | |
| SCHEMBL3695268 | 0.75 | ACMSD (0.70) | PPARASTING1MCL1ACMSDDHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020148325-A1 | NEUTRAL LXR MODULATORS | PHENEX-FXR GMBH (DE) | 2020-07-23 | — | — | WO | disclosed |
| US-20200131144-A1 | AMINE OR (THIO)AMIDE CONTAINING LXR MODULATORS | PHENEX-FXR GMBH (DE) | 2020-04-30 | — | — | US | disclosed |
| EP-1828107-B1 | HYDROXYBIPHENYL CARBOXYLIC ACIDS AND DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE | SANOFI AVENTIS DEUTSCHLAND (DE) | 2011-09-28 | — | — | EP | disclosed |
| EP-1828107-B1 | HYDROXYBIPHENYL CARBOXYLIC ACIDS AND DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE | SANOFI AVENTIS DEUTSCHLAND (DE) | 2011-09-28 | — | — | EP | disclosed |
| US-7453009-B2 | Hydroxybiphenyl carboxylic acids and derivatives, method for producing the same and their use | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-11-18 | — | — | US | disclosed |
| US-7453009-B2 | Hydroxybiphenyl carboxylic acids and derivatives, method for producing the same and their use | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-11-18 | — | — | US | disclosed |
| US-20080027134-A1 | HYDROXYBIPHENYL CARBOXYLIC ACIDS AND DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-01-31 | — | — | US | disclosed |
| US-20080027134-A1 | HYDROXYBIPHENYL CARBOXYLIC ACIDS AND DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-01-31 | — | — | US | disclosed |
| EP-1828107-A1 | HYDROXYBIPHENYL CARBOXYLIC ACIDS AND DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE | Sanofi-Aventis Deutschland GmbH (DE) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006063697-A1 | HYDROXYBIPHENYL CARBOXYLIC ACIDS AND DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2006-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027134-A1 | HYDROXYBIPHENYL CARBOXYLIC ACIDS AND DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE | GPR119, HACL2, HCAR2 | STAT3 2761/4885PPARA 231/4885STING1 4132/4885 |
| US-20200131144-A1 | AMINE OR (THIO)AMIDE CONTAINING LXR MODULATORS | NR1H2, NR1H3, NR1H4 | STAT3 1485/4885PPARA 34/4885STING1 2769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.