Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 10/20 | 0.73 |
| ▸ | DDB1 | Q16531 | 9/20 | 0.73 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | MMP3 | P08254 | 2/20 | 0.47 |
| ▸ | MMP9 | P14780 | 2/20 | 0.47 |
| ▸ | MMP13 | P45452 | 2/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.45 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.45 |
| ▸ | CTSG | P08311 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24155915 | 0.86 | CRBN (0.59) | CRBNDDB1MMP2MMP9MMP13 | |
| SCHEMBL31674504 | 0.85 | MMP13 (0.54) | CRBNDDB1MMP13NTRK1IGF1R | |
| SCHEMBL31674502 | 0.85 | SCN9A (0.54) | CRBNDDB1MMP2MMP3MMP9 | |
| SCHEMBL21995539 | 0.85 | CRBN (0.52) | CRBNDDB1PLCG1MMP13MGLL | |
| SCHEMBL24155471 | 0.85 | SCN9A (0.54) | CRBNDDB1MMP2MMP3MMP9 | |
| SCHEMBL31674505 | 0.85 | CRBN (0.52) | CRBNDDB1PLCG1MMP13MGLL | |
| SCHEMBL24156356 | 0.85 | CRBN (0.52) | CRBNDDB1LTA4HTDP1 | |
| SCHEMBL24156369 | 0.85 | MMP13 (0.54) | CRBNDDB1MMP13NTRK1IGF1R | |
| SCHEMBL5376083 | 0.85 | CRBN (1.00) | CRBNDDB1ALDH1A1MAPTALOX15 | |
| Hydrochloric Acid SCHEMBL30874155 | 0.83 | CRBN (0.96) | CRBNDDB1ALDH1A1MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210403456-A1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF EPILEPSY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2021-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210403456-A1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF EPILEPSY | SLC6A11, SCN1A, SCN1B | CRBN 3575/4885DDB1 4483/4885PLCG1 3628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.