Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 3/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.40 |
| ▸ | F12 | P00748 | 4/20 | 0.39 |
| ▸ | LDHB | P07195 | 1/20 | 0.39 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | SSTR2 | P30874 | 3/20 | 0.38 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.38 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.38 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.38 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24155488 | 0.87 | CXCR4 (0.40) | VDRCACNA1BCXCR4F12TNFSF11 | |
| SCHEMBL24155284 | 0.81 | TNFSF11 (0.38) | CACNA1BCXCR4F12TNFSF11PLAU | |
| SCHEMBL24155481 | 0.80 | TNFSF11 (0.37) | CACNA1BCXCR4F12TNFSF11PLAU | |
| SCHEMBL25455142 | 0.69 | KEAP1 (0.53) | CACNA1BPLAUSSTR2SSTR1SSTR4 | |
| SCHEMBL18767060 | 0.68 | TNFSF11 (0.48) | CACNA1BTNFSF11PLAUSSTR2SSTR1 | |
| SCHEMBL23351361 | 0.68 | F11 (0.48) | F12 | |
| SCHEMBL16201919 | 0.68 | F12 (0.47) | F12 | |
| SCHEMBL25458001 | 0.67 | CACNA1B (0.46) | CACNA1BPLAUSSTR2SSTR1SSTR4 | |
| SCHEMBL25758456 | 0.67 | ESR1 (0.51) | ESR1 | |
| SCHEMBL18767061 | 0.67 | CSNK2A2 (0.48) | CACNA1BF12TNFSF11PLAUSSTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021263069-A1 | CYCLIC PEPTIDE COMPOUNDS AND METHODS OF USE | LI FENGQIAO (US) | 2021-12-30 | — | — | WO | disclosed |