Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFSF11 | O14788 | 1/20 | 0.37 |
| ▸ | TFPI | P10646 | 4/20 | 0.37 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.37 |
| ▸ | SSTR2 | P30874 | 2/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.37 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.37 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.37 |
| ▸ | TSLP | Q969D9 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | F12 | P00748 | 2/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
| ▸ | F11 | P03951 | 2/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24155284 | 0.93 | TNFSF11 (0.38) | TNFSF11TFPISSTR1SSTR2SSTR4 | |
| SCHEMBL24155488 | 0.93 | CXCR4 (0.40) | TNFSF11TFPISSTR1SSTR2SSTR4 | |
| SCHEMBL25758456 | 0.80 | ESR1 (0.51) | ESR1 | |
| SCHEMBL24155857 | 0.80 | VDR (0.45) | TNFSF11SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL19545700 | 0.62 | KDM1A (0.69) | SSTR2SSTR4SSTR3SSTR5KLK7 | |
| SCHEMBL13955093 | 0.61 | ITGB3 (0.46) | TSLPPLAU | |
| SCHEMBL18767060 | 0.59 | TNFSF11 (0.48) | TNFSF11SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL25758366 | 0.59 | NPY4R (0.37) | TFPI | |
| SCHEMBL25758263 | 0.59 | TFPI (0.40) | TFPI | |
| SCHEMBL14003237 | 0.59 | TUBB4A (0.58) | TSLPF12KLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021263069-A1 | CYCLIC PEPTIDE COMPOUNDS AND METHODS OF USE | LI FENGQIAO (US) | 2021-12-30 | — | — | WO | disclosed |