Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 19/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24727594 | 0.84 | RBP4 (0.52) | RBP4 | |
| SCHEMBL2781457 | 0.84 | DRD2 (0.56) | RBP4 | |
| SCHEMBL2782833 | 0.84 | RBP4 (0.54) | RBP4CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL24727974 | 0.83 | RBP4 (0.45) | RBP4CYP2D6 | |
| SCHEMBL5501124 | 0.81 | DRD2 (0.52) | RBP4 | |
| SCHEMBL2783595 | 0.81 | RBP4 (0.58) | RBP4 | |
| SCHEMBL17224411 | 0.81 | RBP4 (0.45) | RBP4CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL28146212 | 0.81 | RBP4 (0.55) | RBP4CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL29915616 | 0.81 | RBP4 (0.45) | RBP4CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL3768131 | 0.80 | HTR6 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3137168-B1 | SUBSTITUTED 4-PHENYLPIPERIDINES, THEIR PREPARATION AND USE | UNIV COLUMBIA (US) | 2022-01-05 | — | — | EP | disclosed |