SCHEMBL24158366

SCHEMBL24158366

OC(c1ccccc1)(c1cccc(Cl)c1)c1ccccc1-c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 5/20 0.46
KIF11 P52732 4/20 0.38
CYP3A4 P08684 2/20 0.38
CYP3A5 P20815 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.37
ALDH1A1 P00352 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
PGR P06401 1/20 0.37
PDK2 Q15119 1/20 0.37
CYP2A6 P11509 1/20 0.36
CRHBP P24387 1/20 0.36
CRHR2 Q13324 1/20 0.36
RORC P51449 1/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
TP53 P04637 1/20 0.35
TSHR P16473 1/20 0.35
NFKB1 P19838 1/20 0.35
NFKB2 Q00653 1/20 0.35
RELA Q04206 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26753540 0.87 CYP1A2 (0.43) CYP19A1CYP3A4CYP3A5PDK2RORC
SCHEMBL4946065 0.85 CRHBP (0.44) CYP3A4CYP3A5ALDH1A1CYP2A6CRHBP
SCHEMBL20323244 0.84 RORC (0.44) CYP19A1CYP3A4CYP3A5RORCNPC1
SCHEMBL2394054 0.81 CYP19A1 (0.62) CYP19A1KIF11L3MBTL1RORCTSHR
SCHEMBL30791490 0.81 CYP19A1 (0.62) CYP19A1KIF11L3MBTL1RORCTSHR
SCHEMBL2390681 0.81 CYP19A1 (0.62) CYP19A1KIF11L3MBTL1RORCTSHR
SCHEMBL20323180 0.81 CYP19A1 (0.60) CYP19A1CYP3A4CYP3A5RORC
SCHEMBL22114521 0.79 KCNN4 (0.44) CYP19A1KIF11ALDH1A1PDK2HTT
SCHEMBL24329306 0.79 CYP3A4 (0.42) CYP19A1CYP3A4CYP3A5TDP1CYP2A6
SCHEMBL20323235 0.78 SMN1; SMN2 (0.44) CYP19A1L3MBTL1RORCNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3932927-B1 METAL COMPLEX AND COMPOSITION INCLUDING SAID METAL COMPLEX SUMITOMO CHEMICAL CO (JP) 2023-09-27 EP disclosed
EP-3932927-A1 METAL COMPLEX AND COMPOSITION INCLUDING SAID METAL COMPLEX SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2022-01-05 EP disclosed