SCHEMBL4946065

SCHEMBL4946065

OC(c1ccccc1)(c1ccccc1)c1ccccc1-c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRHBP P24387 1/20 0.44
CRHR2 Q13324 1/20 0.44
HSD17B10 Q99714 3/20 0.43
ALDH1A1 P00352 3/20 0.43
HPGD P15428 2/20 0.43
BCL2L1 Q07817 1/20 0.43
CYP2C9 P11712 3/20 0.41
BACE1 P56817 1/20 0.39
CYP2D6 P10635 2/20 0.39
CYP1A2 P05177 2/20 0.39
CYP2C19 P33261 2/20 0.39
HIF1A Q16665 1/20 0.39
CYP2A6 P11509 1/20 0.38
MAPK1 P28482 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
BCAT2 O15382 1/20 0.36
CYP3A4 P08684 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9285749 0.89 ALDH1A1 (0.42) CRHBPCRHR2HSD17B10ALDH1A1HPGD
SCHEMBL11392792 0.89 RORC (0.43) CRHBPCRHR2ALDH1A1CYP3A4CYP3A5
SCHEMBL1758324 0.89 CRHBP (0.48) CRHBPCRHR2HSD17B10ALDH1A1HPGD
SCHEMBL18073333 0.85 LMNA (0.43) CRHBPCRHR2HSD17B10ALDH1A1HPGD
SCHEMBL24158366 0.85 CYP19A1 (0.46) CRHBPCRHR2ALDH1A1CYP2A6CYP3A4
SCHEMBL22114521 0.82 KCNN4 (0.44) ALDH1A1
SCHEMBL30444974 0.81 CYP19A1 (0.47) CRHBPCRHR2HSD17B10ALDH1A1HPGD
SCHEMBL26753540 0.81 CYP1A2 (0.43) CYP1A2CYP3A4CYP3A5
SCHEMBL11591149 0.81 CRHBP (0.53) CRHBPCRHR2HSD17B10ALDH1A1HPGD
SCHEMBL1191671 0.80 CRHBP (0.35) CRHBPCRHR2HSD17B10ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11566033-B2 Compound and an organic semiconducting layer comprising the same NOVALED GMBH (DE) 2023-01-31 US disclosed
US-20200339614-A1 Compound and an Organic Semiconducting Layer Comprising the Same NOVALED GMBH (DE) 2020-10-29 US disclosed
US-7462405-B2 Organic element for electroluminescent devices EASTMAN KODAK COMPANY (US) 2008-12-09 US disclosed
US-7462405-B2 Organic element for electroluminescent devices EASTMAN KODAK COMPANY (US) 2008-12-09 US disclosed
US-20050136286-A1 Organic element for electroluminescent devices GLOBAL OLED TECHNOLOGY LLC 2005-06-23 US disclosed
US-20050123790-A1 Organic element for electroluminescent devices EASTMAN KODAK COMPANY 2005-06-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11566033-B2 Compound and an organic semiconducting layer comprising the same NR2E3, NR2C2, C1R CRHBP 3449/4885CRHR2 224/4885HSD17B10 1449/4885
US-20200339614-A1 Compound and an Organic Semiconducting Layer Comprising the Same NR2E3, C3AR1, C1R CRHBP 3817/4885CRHR2 211/4885HSD17B10 914/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.