SCHEMBL2416144

SCHEMBL2416144

CCCCCCc1ccccc1C(=O)OCC

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.61
ALDH1A1 P00352 5/20 0.59
LMNA P02545 1/20 0.59
TP53 P04637 1/20 0.57
CYP3A4 P08684 1/20 0.57
MAPK1 P28482 1/20 0.57
TDP1 Q9NUW8 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
HSD17B10 Q99714 3/20 0.53
KDM4E B2RXH2 2/20 0.52
POLB P06746 1/20 0.52
LIPG Q9Y5X9 1/20 0.50
PRSS1 P07477 1/20 0.50
PRSS2 P07478 1/20 0.50
PRSS3 P35030 1/20 0.50
NOD2 Q9HC29 1/20 0.49
THRA P10827 1/20 0.49
THRB P10828 1/20 0.49
CYP4F2 P78329 1/20 0.49
CYP4A11 Q02928 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3949422 1.00 TSHR (0.61) TSHRALDH1A1LMNATP53CYP3A4
SCHEMBL29089577 1.00 TSHR (0.61) TSHRALDH1A1LMNATP53CYP3A4
SCHEMBL7782804 0.98 TSHR (0.62) TSHRALDH1A1LMNATP53CYP3A4
Benzene SCHEMBL27466115 0.97 TSHR (0.57) TSHRALDH1A1LMNATP53CYP3A4
SCHEMBL1791133 0.94 TSHR (0.65) TSHRALDH1A1LMNATP53CYP3A4
SCHEMBL2385142 0.89 ALDH1A1 (0.77) TSHRALDH1A1LMNATP53CYP3A4
SCHEMBL11220190 0.89 TSHR (0.59) TSHRALDH1A1LMNATP53CYP3A4
SCHEMBL21800979 0.89 ALDH1A1 (0.77) TSHRALDH1A1LMNATP53CYP3A4
SCHEMBL2385137 0.89 ALDH1A1 (0.77) TSHRALDH1A1LMNATP53CYP3A4
SCHEMBL1147852 0.89 ALDH1A1 (0.77) TSHRALDH1A1LMNATP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113827507-A Sunscreen composition capable of phase inversion in use, preparation method and sunscreen cosmetic 南京阿奴生物科技有限公司 2021-12-24 CN claimed
US-12636242-B2 Increased solubilization of diethylamino hydroxybenzoyl hexyl benzoate DSM IP ASSETS B.V. (NL) 2026-05-26 US disclosed
US-20250221915-A1 IMPROVEMENT OF THE WATER RESISTANCE OF COSMETIC COMPOSITIONS COMPRISING UV FILTERS TOTALENERGIES ONETECH (FR) 2025-07-10 US disclosed
EP-4504132-A1 IMPROVEMENT OF THE WATER RESISTANCE OF COSMETIC COMPOSITIONS COMPRISING UV FILTERS DSM IP Assets B.V. (NL) 2025-02-12 EP disclosed
US-20240041732-A1 INCREASED SOLUBILIZATION OF DIETHYLAMINO HYDROXYBENZOYL HEXYL BENZOATE TOTALENERGIES ONETECH (FR) 2024-02-08 US disclosed
WO-2023194290-A1 IMPROVEMENT OF THE WATER RESISTANCE OF COSMETIC COMPOSITIONS COMPRISING UV FILTERS DSM IP ASSETS B.V. (NL) 2023-10-12 WO disclosed
EP-2300532-B1 PVC-BASED FLAME-RETARDANT COMPOSITION PORCHER IND (FR) 2022-11-09 EP disclosed
EP-3897527-A1 OXIDATIVE DYE IN RED SHADES WITH IMPROVED FASTNESS AND IMPROVED HOMOGENEITY Henkel AG & Co. KGaA (DE) 2021-10-27 EP disclosed
EP-3704134-A1 ANTIMICROBIAL TETRAPEPTIDES DSM IP Assets B.V. (NL) 2020-09-09 EP disclosed
WO-2020126225-A1 OXIDATIVE DYE IN RED SHADES WITH IMPROVED FASTNESS AND IMPROVED HOMOGENEITY HENKEL AG & CO. KGAA (DE) 2020-06-25 WO disclosed
US-20070020455-A1 Process for creating fabrics with branched fibrils and such fibrillated fabrics SAGE AUTOMOTIVE INTERIORS, INC. 2007-01-25 US disclosed
WO-2006078835-A1 PROCESS FOR CREATING FABRICS WITH BRANCHED FIBRILS AND SUCH FIBRILLATED FABRICS MILLIKEN & COMPANY (US) 2006-07-27 WO disclosed
US-20060166578-A1 Process for creating fabrics with branched fibrils and such fibrillated fabrics MILLIKEN & COMPANY 2006-07-27 US disclosed
EP-1421139-A2 HIGHER ALKYLATED TRIARYL PHOSPHATE ESTER FLAME RETARDANTS Pabu Services, Inc. (US) 2004-05-26 EP disclosed
US-6667355-B2 Adding a mixture comprising triaryl phosphate esters to polyurethane for imparting flame retardant properties PABU SERVICES, INC. 2003-12-23 US disclosed
US-20030078325-A1 Higher alkylated triaryl phosphate ester flame retardants CHEMTURA USA CORPORATION 2003-04-24 US disclosed
WO-2003020809-A2 HIGHER ALKYLATED TRIARYL PHOSPHATE ESTER FLAME RETARDANTS PABU SERVICES, INC. (US) 2003-03-13 WO disclosed
US-5961998-A Glossy composition containing aromatic oils thickened by a polysaccharide ether L'OREAL (FR) 1999-10-05 US disclosed
EP-0534283-B1 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO LTD (JP) 1997-12-17 EP disclosed
US-5290676-A Methine dye sensitizers, controlling size and shape of silver halide grains FUJI PHOTO FILM CO., LTD. (JP) 1994-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250221915-A1 IMPROVEMENT OF THE WATER RESISTANCE OF COSMETIC COMPOSITIONS COMPRISING UV FILTERS C1R, CAPRIN1, CYP51A1 TSHR 4390/4885ALDH1A1 1512/4885LMNA 750/4885
US-20240041732-A1 INCREASED SOLUBILIZATION OF DIETHYLAMINO HYDROXYBENZOYL HEXYL BENZOATE CDC73, CYP51A1, BCAS2 TSHR 4202/4885ALDH1A1 1350/4885LMNA 912/4885
US-12636242-B2 Increased solubilization of diethylamino hydroxybenzoyl hexyl benzoate SCD, CUTA, TRPA1 TSHR 2733/4885ALDH1A1 167/4885LMNA 1452/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.