Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5005950 | 0.88 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL2412644 | 0.88 | CHRM5 (0.35) | CTSKL3MBTL1ALDH1A1PTGDR2PDE4A | |
| SCHEMBL2411195 | 0.87 | PTGDR2 (0.31) | CTSKL3MBTL1ALDH1A1PTGDR2 | |
| SCHEMBL2406679 | 0.85 | PTGDR2 (0.34) | CTSKL3MBTL1PTGDR2PDE4APDE4B | |
| SCHEMBL2410005 | 0.85 | PTGDR2 (0.34) | CTSKL3MBTL1ALDH1A1PTGDR2PDE4A | |
| SCHEMBL2414633 | 0.85 | PTGDR2 (0.32) | CTSKL3MBTL1PTGDR2PDE4APDE4B | |
| SCHEMBL2409830 | 0.85 | PTGDR2 (0.39) | CTSKL3MBTL1PTGDR2 | |
| SCHEMBL2410591 | 0.85 | PTGDR2 (0.33) | L3MBTL1PTGDR2PDE4APDE4BPDE4C | |
| SCHEMBL2410366 | 0.84 | ALDH1A1 (0.38) | ALDH1A1PTGDR2PDE4APDE4BPDE4C | |
| SCHEMBL2416581 | 0.83 | HTR2C (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |
| EP-2114917-A2 | PYRROLE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008108380-A2 | PYRROLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-09-12 | — | — | WO | disclosed |