SCHEMBL24166409

SCHEMBL24166409

Clc1cc2cc(-c3cccc4c3-c3ccccc3[Si]43c4ccccc4-c4ccccc43)ccc2c2ccccc12

nearest known ligand 0.31

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.31
KDM4E B2RXH2 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2C19 P33261 1/20 0.30
RAB9A P51151 1/20 0.30
ATM Q13315 1/20 0.30
HSD17B10 Q99714 1/20 0.30
BACE1 P56817 1/20 0.30
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27394841 0.82 CYP1A2 (0.37) ALDH1A1KDM4ECYP1A2CYP2C19RAB9A
SCHEMBL24166745 0.81 PTGES (0.32)
SCHEMBL31229409 0.77 ALDH1A1 (0.44) ALDH1A1KDM4ECYP1A2CYP2C19RAB9A
SCHEMBL27394837 0.75 CYP2A6 (0.37) CYP1A2BACE1TRPA1
SCHEMBL27394605 0.70 CYP2A6 (0.39) ALDH1A1CYP1A2RAB9A
SCHEMBL24166773 0.69 CYP2A6 (0.37) ALDH1A1CYP1A2RAB9A
SCHEMBL20800833 0.69 HPRT1 (0.48) ALDH1A1CYP1A2CYP2C19HSD17B10
SCHEMBL21453541 0.69 KDM4E (0.34) ALDH1A1KDM4E
SCHEMBL31229554 0.69 HPRT1 (0.46) ALDH1A1
SCHEMBL22947709 0.69 CYP1A2 (0.41) ALDH1A1KDM4ECYP1A2CYP2C19RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022004994-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME 덕산네오룩스 주식회사 2022-01-06 WO disclosed