SCHEMBL27394841

SCHEMBL27394841

Clc1cc(-c2cccc3c2-c2ccccc2[Si]32c3ccccc3-c3ccccc32)cc2ccccc12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.37
CYP2A6 P11509 1/20 0.37
ALDH1A1 P00352 2/20 0.35
HSD17B10 Q99714 2/20 0.35
KDM4E B2RXH2 1/20 0.35
CYP2C19 P33261 1/20 0.35
RAB9A P51151 1/20 0.35
ATM Q13315 1/20 0.35
HSD17B1 P14061 1/20 0.34
HSD17B2 P37059 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
CASP1 P29466 1/20 0.33
HIF1A Q16665 1/20 0.33
CES1 P23141 1/20 0.32
CCR1 P32246 1/20 0.30
CCR8 P51685 1/20 0.30
ALOX5 P09917 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24166409 0.82 ALDH1A1 (0.31) CYP1A2ALDH1A1HSD17B10KDM4ECYP2C19
SCHEMBL27394837 0.79 CYP2A6 (0.37) CYP1A2CYP2A6HSD17B1HSD17B2
SCHEMBL24166745 0.73 PTGES (0.32)
SCHEMBL27394605 0.73 CYP2A6 (0.39) CYP1A2CYP2A6ALDH1A1RAB9AHPGD
SCHEMBL24166773 0.72 CYP2A6 (0.37) CYP1A2CYP2A6ALDH1A1RAB9AHPGD
SCHEMBL26021833 0.71 CYP11B1 (0.49) CYP1A2CYP2A6ALDH1A1HSD17B10KDM4E
SCHEMBL25125419 0.71 CYP1A2 (0.42) CYP1A2CYP2A6ALDH1A1HSD17B10KDM4E
SCHEMBL20800825 0.70 DNMT1 (0.43) CYP1A2CYP2A6ALDH1A1HSD17B10KDM4E
SCHEMBL20800843 0.69 DNMT1 (0.46) CYP1A2CYP2A6ALDH1A1HSD17B10KDM4E
SCHEMBL22947709 0.69 CYP1A2 (0.41) CYP1A2CYP2A6ALDH1A1HSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024096578-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE HAVING SAME 덕산네오룩스 주식회사 2024-05-10 WO disclosed