Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Racemethionine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BHMT | Q93088 | 11/20 | 0.49 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.49 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.47 |
| ▸ | NOS2 | P35228 | 3/20 | 0.45 |
| ▸ | NOS3 | P29474 | 2/20 | 0.45 |
| ▸ | NOS1 | P29475 | 2/20 | 0.45 |
| ▸ | GRM8 | O00222 | 1/20 | 0.42 |
| ▸ | GRM6 | O15303 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GSR | P00390 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.42 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methionine SCHEMBL2416707 | 1.00 | BHMT (0.49) | BHMTBHMT2RNPEPNOS2NOS3 | |
| Racemethionine SCHEMBL23113875 | 0.98 | BHMT (0.47) | BHMTBHMT2RNPEPNOS2NOS3 | |
| Methionine SCHEMBL29009467 | 0.92 | BHMT (0.49) | BHMTBHMT2RNPEPNOS2NOS3 | |
| Racemethionine SCHEMBL23647354 | 0.92 | BHMT (0.49) | BHMTBHMT2RNPEPNOS2NOS3 | |
| Racemethionine SCHEMBL5617580 | 0.90 | BHMT (0.57) | BHMTBHMT2RNPEPNOS2NOS3 | |
| Racemethionine SCHEMBL23361954 | 0.90 | BHMT (0.57) | BHMTBHMT2RNPEPNOS2NOS3 | |
| Methionine SCHEMBL5584463 | 0.90 | BHMT (0.57) | BHMTBHMT2RNPEPNOS2NOS3 | |
| Racemethionine SCHEMBL126688 | 0.90 | — | — | |
| Racemethionine SCHEMBL287590 | 0.90 | BHMT (0.57) | BHMTBHMT2RNPEPNOS2NOS3 | |
| Methionine SCHEMBL4226 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4784999-B2 | — | — | 2011-10-05 | — | — | JP | claimed |
| US-7759419-B2 | Corrosion resistant coatings | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2010-07-20 | — | — | US | claimed |
| EP-1587884-A2 | CORROSION RESISTANT COATINGS CONTAINING RARE EARTH COMPOUNDS | University of Missouri Curators, Office of Tech. & Spec. Projects (US) | 2005-10-26 | — | — | EP | claimed |
| US-20040249043-A1 | Rare earth metals for coatings with acid extenders, magnesium sulfate, calcium sulfate, barium sulfate, strontium sulfate, samarium sulfate with inorganic polymers and metal oxides | CURATORS OF THE UNIVERSITY OF MISSOURI, THE | 2004-12-09 | — | — | US | claimed |
| US-20040249023-A1 | Compounds for corrosion resistant primer coatings and protection of metal substrates | CURATORS OF THE UNIVERSITY OF MISSOURI, THE | 2004-12-09 | — | — | US | claimed |
| WO-2004065497-A2 | CORROSION RESISTANT COATINGS CONTAINING RARE EARTH COMPOUNDS | UNIVERSITY OF MISSOURI CURATORS (US) | 2004-08-05 | — | — | WO | claimed |
| CN-104395479-B | Biomarkers for diabetes | 香港中文大学 | 2019-03-15 | — | — | CN | disclosed |
| EP-2368945-A2 | Corrosion resistant coatings | University of Missouri Curators (US) | 2011-09-28 | — | — | EP | disclosed |
| CN-101072789-A | O-linked glycosylation of peptides | NEOSE TECHNOLOGIES INC (US) | 2007-11-14 | — | — | CN | disclosed |