Methionine

Methionine

SCHEMBL5584463

CSCC[C@H](N)C(=O)O.CSCC[C@H](N)C(=O)O.CSCC[C@H](N)C(=O)O.CSCC[C@H](N)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BHMT Q93088 10/20 0.57
BHMT2 Q9H2M3 1/20 0.57
RNPEP Q9H4A4 1/20 0.56
NOS2 P35228 3/20 0.52
NOS3 P29474 2/20 0.52
NOS1 P29475 2/20 0.52
GRM8 O00222 1/20 0.50
GRM6 O15303 1/20 0.50
GRIN2D O15399 1/20 0.50
GRIN3B O60391 1/20 0.50
GSR P00390 1/20 0.50
CYP1A2 P05177 1/20 0.50
GRIK1 P39086 1/20 0.50
GRM5 P41594 1/20 0.50
GRIA1 P42261 1/20 0.50
GRIA2 P42262 1/20 0.50
GRIA3 P42263 1/20 0.50
SLC1A3 P43003 1/20 0.50
SLC1A2 P43004 1/20 0.50
SLC1A1 P43005 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Racemethionine SCHEMBL16062299 1.00 BHMT (0.57) BHMTBHMT2RNPEPNOS2NOS3
Methionine SCHEMBL162030 1.00 BHMT (0.57) BHMTBHMT2RNPEPNOS2NOS3
Racemethionine SCHEMBL9504290 1.00
Racemethionine SCHEMBL5617580 1.00 BHMT (0.57) BHMTBHMT2RNPEPNOS2NOS3
Racemethionine SCHEMBL8983115 1.00 BHMT (0.57) BHMTBHMT2RNPEPNOS2NOS3
Racemethionine SCHEMBL23361954 1.00 BHMT (0.57) BHMTBHMT2RNPEPNOS2NOS3
Racemethionine SCHEMBL287590 1.00 BHMT (0.57) BHMTBHMT2RNPEPNOS2NOS3
Methionine SCHEMBL4226 1.00
Racemethionine SCHEMBL126688 1.00
Racemethionine SCHEMBL31367634 1.00

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1737734-A2 COATED IMPLANTS, THEIR MANUFACTURING AND USE THEREOF Scil Technology GmbH (DE) 2007-01-03 EP disclosed
WO-2005089829-A2 COATED IMPLANTS, THEIR MANUFACTURING AND USE THEREOF SCIL TECHNOLOGY GMBH (DE) 2005-09-29 WO disclosed