Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19423042 | 0.83 | ALDH1A1 (0.46) | KDM4EALDH1A1TP53MEN1KMT2A | |
| SCHEMBL7044788 | 0.77 | TSHR (0.51) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL19423136 | 0.77 | GAA (0.44) | KDM4EALDH1A1HTTMEN1KMT2A | |
| SCHEMBL1336945 | 0.76 | POLB (0.50) | ALDH1A1TP53MEN1KMT2ATUBB4A | |
| SCHEMBL17846127 | 0.76 | LMNA (0.49) | KDM4EALDH1A1HTTTUBB4ATUBB | |
| SCHEMBL7350723 | 0.75 | ACKR3 (0.54) | KDM4EALDH1A1HTTMEN1KMT2A | |
| SCHEMBL9525689 | 0.75 | KMT2A (0.51) | KDM4EALDH1A1HTTMEN1KMT2A | |
| SCHEMBL8803946 | 0.72 | AOC3 (0.43) | KDM4EALDH1A1HTTMEN1KMT2A | |
| SCHEMBL30958894 | 0.71 | POLB (0.62) | TP53MEN1KMT2ALPAR1TUBB4A | |
| Hydrochloric Acid SCHEMBL8805153 | 0.71 | AOC3 (0.42) | KDM4EALDH1A1HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3438105-B1 | DIARYL- -LACTAM COMPOUND AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF | UNIV FUDAN (CN) | 2022-01-05 | — | — | EP | disclosed |