Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 3/20 | 0.50 |
| ▸ | KDM4A | O75164 | 2/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.50 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.50 |
| ▸ | TET3 | O43151 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | GABRP | O00591 | 2/20 | 0.42 |
| ▸ | GABRD | O14764 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.42 |
| ▸ | GABRE | P78334 | 2/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25492943 | 1.00 | TET2 (0.50) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL10599631 | 0.89 | TET2 (0.60) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL1244924 | 0.85 | CAMK2A (0.46) | TET2KDM4AKDM4CKDM2ALMNA | |
| SCHEMBL12355088 | 0.85 | CAMK2A (0.46) | TET2KDM4AKDM4CKDM2ALMNA | |
| SCHEMBL3687001 | 0.85 | PDE4A (0.54) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL16600592 | 0.85 | PDE4A (0.48) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL16600326 | 0.84 | TET2 (0.50) | TET2KDM4AKDM4CKDM2ATET3 | |
| SCHEMBL2473072 | 0.83 | LMNA (0.50) | LMNAENPEPNFKB1 | |
| SCHEMBL15153687 | 0.83 | LMNA (0.50) | LMNAENPEPNFKB1 | |
| SCHEMBL28908459 | 0.83 | PDE4A (0.52) | TET2KDM4AKDM4CKDM2ATET3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250223392-A1 | HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF | ALCON INC (CH) | 2025-07-10 | — | — | US | disclosed |
| US-12286501-B2 | Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof | ALCON INC. (CH) | 2025-04-29 | — | — | US | disclosed |
| US-20250127925-A1 | DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO | HERCULES CAPITAL, INC. | 2025-04-24 | — | — | US | disclosed |
| US-20250059330-A1 | SILICONE HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2025-02-20 | — | — | US | disclosed |
| EP-4481478-A2 | SILICONE HYDROGEL CONTACT LENSES | Alcon Inc. (CH) | 2024-12-25 | — | — | EP | disclosed |
| US-12162987-B2 | Silicone hydrogel contact lenses | ALCON INC. (CH) | 2024-12-10 | — | — | US | disclosed |
| EP-4235274-B1 | SILICONE HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2024-10-09 | — | — | EP | disclosed |
| US-12076418-B2 | Dually derivatized chitosan nanoparticles and methods of making and using the same for gene transfer in vivo | ENGENE, INC. (CA) | 2024-09-03 | — | — | US | disclosed |
| US-20240254269-A1 | HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF | ALCON INC. (CH) | 2024-08-01 | — | — | US | disclosed |
| US-11926689-B2 | Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof | ALCON INC. (CH) | 2024-03-12 | — | — | US | disclosed |
| EP-3390498-A1 | HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF | Novartis AG (CH) | 2018-10-24 | — | — | EP | disclosed |
| US-10081697-B2 | Hydrophilized polydiorganosiloxane vinylic crosslinkers and uses thereof | NOVARTIS AG (CH) | 2018-09-25 | — | — | US | disclosed |
| EP-3231789-A1 | BIOMARKERS FOR DIAGNOSING MULTIPLE SCLEROSIS, AND METHODS THEREOF | Phenomenome Discoveries Inc. (CA) | 2017-10-18 | — | — | EP | disclosed |
| WO-2017103790-A1 | HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF | NOVARTIS AG (CH) | 2017-06-22 | — | — | WO | disclosed |
| US-20170166673-A1 | HYDROPHILIZED POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS AND USES THEREOF | ALCON INC. (CH) | 2017-06-15 | — | — | US | disclosed |
| US-20160235863-A1 | DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO | HERCULES CAPITAL, INC. | 2016-08-18 | — | — | US | disclosed |
| US-20140024132-A1 | METHODS AND SYSTEMS USING INTEGRATED METABOLOMICS AND PHARMACOKINETICS FOR MULTI-COMPONENT DRUG EVALUATION | THE UNIVERSITY OF NORTH CAROLINA AT GREENSBORO | 2014-01-23 | — | — | US | disclosed |
| EP-2396009-A1 | COMPOSITIONS FOR THE TREATMENT OF APHTHOUS STOMATITIS | Bonucci, Monica (IT) | 2011-12-21 | — | — | EP | disclosed |
| WO-2011113066-A1 | METHODS AND SYSTEMS USING INTEGRATED METABOLOMICS AND PHARMACOKINETICS FOR MULTI-COMPONENT DRUG EVALUATION | THE UNIVERSITY OF NORTH CAROLINA AT GREENSBORO (US) | 2011-09-15 | — | — | WO | disclosed |
| WO-2010092534-A1 | COMPOSITIONS FOR THE TREATMENT OF APHTHOUS STOMATITIS | BONUCCI MONICA (IT) | 2010-08-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250127925-A1 | DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO | CSGALNACT1, CHI3L2, LNPEP | TET2 420/4885KDM4A 1237/4885KDM4C 1496/4885 |
| US-12076418-B2 | Dually derivatized chitosan nanoparticles and methods of making and using the same for gene transfer in vivo | CSGALNACT1, CHI3L2, LNPEP | TET2 420/4885KDM4A 1237/4885KDM4C 1496/4885 |
| US-20160235863-A1 | DUALLY DERIVATIZED CHITOSAN NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME FOR GENE TRANSFER IN VIVO | CSGALNACT1, CHI3L2, LNPEP | TET2 420/4885KDM4A 1237/4885KDM4C 1496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.