Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.31 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26618043 | 0.84 | DGAT1 (0.36) | DGAT1KDM1AKDM1BNOX1 | |
| SCHEMBL20263273 | 0.79 | CA3 (0.38) | KDM1AKDM1B | |
| SCHEMBL30280670 | 0.79 | CA3 (0.38) | KDM1AKDM1B | |
| SCHEMBL28493663 | 0.76 | KDM4E (0.37) | NOX1 | |
| SCHEMBL22914962 | 0.76 | ESR1 (0.33) | — | |
| SCHEMBL31408842 | 0.76 | — | — | |
| SCHEMBL30402438 | 0.75 | ALOX15 (0.38) | NOX1 | |
| SCHEMBL15897331 | 0.73 | KDM1A (0.32) | KDM1AKDM1B | |
| SCHEMBL26915320 | 0.73 | PDE2A (0.42) | — | |
| SCHEMBL10091983 | 0.72 | DGAT1 (0.39) | DGAT1KDM1AKDM1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3717471-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASES | GALAPAGOS NV (BE) | 2022-01-05 | — | — | EP | disclosed |