Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 5/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.38 |
| ▸ | PDE1A | P54750 | 5/20 | 0.35 |
| ▸ | PDE1B | Q01064 | 5/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 5/20 | 0.35 |
| ▸ | PDE1C | Q14123 | 5/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.35 |
| ▸ | PDE5A | O76074 | 4/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1225856 | 0.80 | ACHE (0.46) | PDE4APDE4BPDE4CPDE4DPDE1A | |
| SCHEMBL1047858 | 0.73 | ALDH1A1 (0.46) | PDE4APDE4BPDE4CPDE4DCYP3A4 | |
| SCHEMBL31207104 | 0.73 | CYP3A4 (0.56) | PDE4APDE4BPDE4CPDE4DMMP1 | |
| SCHEMBL19681303 | 0.73 | ACHE (0.36) | CYP3A4TAAR1CA2CA4ACHE | |
| SCHEMBL8130587 | 0.72 | MEN1 (0.47) | PDE4APDE4BPDE4CPDE4DPDE1A | |
| SCHEMBL18277345 | 0.71 | PDE4A (0.43) | PDE4APDE4BPDE4CPDE4DPDE1A | |
| SCHEMBL18295990 | 0.71 | PDE4A (0.43) | PDE4APDE4BPDE4CPDE4DPDE1A | |
| SCHEMBL23783141 | 0.71 | ERN1 (0.44) | PDE4APDE4BPDE4CPDE4DCA2 | |
| SCHEMBL28596719 | 0.71 | ACHE (0.45) | PDE4APDE4BPDE4CPDE4DPDE1A | |
| SCHEMBL31289582 | 0.70 | PDE1A (0.42) | PDE4APDE4BPDE4CPDE4DPDE1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3717471-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASES | GALAPAGOS NV (BE) | 2022-01-05 | — | — | EP | disclosed |