Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | PDE1A | P54750 | 1/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9596755 | 0.82 | PDE4A (0.48) | ACHEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL31289582 | 0.81 | PDE1A (0.42) | ACHEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10755095 | 0.81 | ACHE (0.48) | ACHEERN1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL24169437 | 0.80 | PDE4A (0.38) | ACHEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL95192 | 0.79 | HRH3 (0.40) | ACHEALDH1A1MAPTKDM4E | |
| SCHEMBL510321 | 0.77 | KDM4E (0.47) | ACHEERN1SMN1; SMN2ALDH1A1PKM | |
| SCHEMBL31187890 | 0.77 | ACHE (0.48) | ACHEPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL20563298 | 0.76 | TAAR1 (0.50) | ACHEKDM4E | |
| SCHEMBL10752271 | 0.76 | ALOX5 (0.44) | ACHE | |
| SCHEMBL6921814 | 0.76 | ALDH1A1 (0.45) | ACHEERN1SMN1; SMN2ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334175-B1 | PHENYL-SUBSTITUTED BICYCLOOCTANE 1,3 DIONE DERIVATIVES | BAYER IP GMBH (DE) | 2017-03-01 | — | — | EP | disclosed |
| US-8367873-B2 | Phenyl-substituted bicyclooctane-1,3-dione derivatives | BAYER CROPSCIENCE AG (DE) | 2013-02-05 | — | — | US | disclosed |
| US-20110039701-A1 | Phenyl-substituted Bicyclooctane-1,3-dione Derivatives | BAYER CROPSCIENCE AG (DE) | 2011-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110039701-A1 | Phenyl-substituted Bicyclooctane-1,3-dione Derivatives | DDT, PIP5K1B, PIP5K1C | ACHE 262/4885PDE4A 2084/4885PDE4B 1735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.