Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.41 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15846539 | 1.00 | FDPS (0.57) | FDPSLMNAGPR84SPHK1FFAR1 | |
| SCHEMBL30407916 | 0.97 | FDPS (0.61) | FDPSLMNAGPR84SPHK1FFAR1 | |
| SCHEMBL29176608 | 0.97 | FDPS (0.61) | FDPSLMNAGPR84SPHK1FFAR1 | |
| SCHEMBL23467125 | 0.92 | FDPS (0.50) | FDPSLMNAGPR84SPHK1FFAR1 | |
| SCHEMBL30393500 | 0.86 | FDPS (0.50) | FDPSLMNAGPR84SPHK1FFAR1 | |
| SCHEMBL28727004 | 0.85 | LMNA (0.50) | FDPSLMNAGPR84SPHK1TSHR | |
| SCHEMBL8890428 | 0.80 | FDPS (0.53) | FDPSLMNAGPR84SPHK1FFAR1 | |
| SCHEMBL31512569 | 0.80 | FDPS (0.53) | FDPSLMNAGPR84SPHK1FFAR1 | |
| SCHEMBL7797304 | 0.80 | FDPS (0.53) | FDPSLMNAGPR84SPHK1FFAR1 | |
| SCHEMBL10456042 | 0.80 | FDPS (0.53) | FDPSLMNAGPR84SPHK1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210403465-A1 | QUINAZOLINYL-INDAZOLE DERIVATIVES AND THEIR USE AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | VIIV Healthcare UK (No.5) Limited (GB) | 2021-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210403465-A1 | QUINAZOLINYL-INDAZOLE DERIVATIVES AND THEIR USE AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | EIF2AK2, IRF3, MAVS | FDPS 669/4885LMNA 3653/4885GPR84 3965/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.