Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24169494 | 0.85 | NOTUM (0.47) | NOTUMMEN1KMT2AAPOBEC3AAPOBEC3G | |
| SCHEMBL24170233 | 0.82 | NOTUM (0.44) | NOTUMMEN1KMT2AAPOBEC3AAPOBEC3G | |
| SCHEMBL12656578 | 0.80 | NOTUM (0.50) | NOTUMMEN1KMT2AKDM4EMAPT | |
| Ammonia Solution, Strong SCHEMBL905929 | 0.78 | NOTUM (0.49) | NOTUMMEN1KMT2AKDM4EMAPT | |
| SCHEMBL24169797 | 0.78 | ALDH1A1 (0.70) | MEN1KMT2AKDM4EMAPTTDP1 | |
| SCHEMBL11206551 | 0.76 | CRHR1 (0.49) | NOTUMMEN1KMT2AAPOBEC3AAPOBEC3G | |
| SCHEMBL12656441 | 0.74 | NOTUM (0.58) | NOTUMMEN1KMT2AKDM4EMAPT | |
| SCHEMBL12656474 | 0.74 | NOTUM (0.44) | NOTUMMEN1KMT2AAPOBEC3AAPOBEC3G | |
| SCHEMBL19172300 | 0.74 | NOTUM (0.51) | NOTUMMEN1KMT2AKDM4EMAPT | |
| SCHEMBL19148304 | 0.71 | MAPT (0.58) | NOTUMMEN1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3405454-B1 | INDOLINE DERIVATIVES, COMPOSITIONS COMPRISING THEM AND USES THEREOF | YISSUM RES DEV CO OF HEBREW UNIV JERUSALEM LTD (IL) | 2021-12-29 | — | — | EP | disclosed |