SCHEMBL241712

SCHEMBL241712

CC(C)C[C@H](NC(=O)[C@@H](N)CCCNC(=N)N)C(N)=O

nearest known ligand 0.64

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 17/20 0.64
▸ NPY1R P25929 11/20 0.64
▸ NPY5R Q15761 10/20 0.64
▸ NPY2R P49146 7/20 0.64
▸ KISS1R Q969F8 1/20 0.41
▸ DPP7 Q9UHL4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL241711 1.00 NPY4R (0.64) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL29947151 0.94 NPY4R (0.70) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL29947137 0.94 NPY4R (0.70) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL29531992 0.91 NPY4R (0.58) NPY4RNPY1RNPY5RNPY2R
SCHEMBL3138301 0.91 NPY4R (0.58) NPY4RNPY1RNPY5RNPY2R
SCHEMBL30958046 0.91 NPY4R (0.58) NPY4RNPY1RNPY5RNPY2R
SCHEMBL29794924 0.91 NPY4R (0.58) NPY4RNPY1RNPY5RNPY2R
SCHEMBL3138312 0.91 NPY4R (0.58) NPY4RNPY1RNPY5RNPY2R
SCHEMBL18758140 0.90 NPY4R (0.59) NPY4RNPY1RNPY5RNPY2RDPP7
SCHEMBL29947050 0.89 NPY4R (0.59) NPY4RNPY1RNPY5RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230046772-A1 CX3CR1-BINDING POLYPEPTIDES COMPRISING IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS ABLYNX N.V. (BE) 2023-02-16 — — US disclosed
EP-2765190-B1 MUTANT Y-GLUTAMYLTRANSFERASE, AND METHOD FOR PRODUCING Y-GLUTAMYLVALYLGLYCINE OR SALT THEREOF AJINOMOTO KK (JP) 2018-05-23 — — EP disclosed
US-9677106-B2 Method for producing gamma-glutamylvalylglycine or a salt thereof AJINOMOTO CO., INC. (JP) 2017-06-13 — — US disclosed
US-9580696-B2 Method for producing γ-glutamylvalylglycine or a salt thereof AJINOMOTO CO., INC. (JP) 2017-02-28 — — US disclosed
US-20160355861-A1 METHOD FOR PRODUCING GAMMA-GLUTAMYLVALYLGLYCINE OR A SALT THEREOF AJINOMOTO CO., INC. (JP) 2016-12-08 — — US disclosed
EP-2298909-B1 Novel peptide-forming enzyme gene AJINOMOTO KK (JP) 2014-10-01 — — EP disclosed
EP-2298908-B1 Novel peptide-forming enzyme gene AJINOMOTO KK (JP) 2014-08-20 — — EP disclosed
EP-2298907-B1 Novel peptide-forming enzyme gene AJINOMOTO KK (JP) 2014-08-20 — — EP disclosed
EP-2765190-A1 MUTANT -GLUTAMYLTRANSFERASE, AND METHOD FOR PRODUCING -GLUTAMYLVALYLGLYCINE OR SALT THEREOF AJINOMOTO CO., INC. (JP) 2014-08-13 — — EP disclosed
US-20140212920-A1 MUTANT GAMMA-GLUTAMYLTRANSFERASE, AND A METHOD FOR PRODUCING GAMMA-GLUTAMYLVALYLGLYCINE OR A SALT THEREOF AJINOMOTO CO., INC. (JP) 2014-07-31 — — US disclosed
WO-2005010196-A1 METHOD FOR PRODUCING DIPEPTIDES AJINOMOTO CO., INC. (JP) 2005-02-03 — — WO disclosed
US-20050019864-A1 Novel peptide-forming enzyme gene AJINOMOTO CO., INC. (JP) 2005-01-27 — — US disclosed
CN-1558947-A Gene of peptide-producing enzyme, and process for producing dipeptide ֮����ʽ���� 2004-12-29 — — CN disclosed
US-20040253665-A1 Novel peptide-producing enzyme, microbe producing the enzyme and method for dipeptide synthesis using them AJINOMOTO CO., INC. (JP) 2004-12-16 — — US disclosed
US-20040219631-A1 Method for producing tripeptides and/or peptides longer than tripeptides AJINOMOTO CO., INC. (JP) 2004-11-04 — — US disclosed
US-20040204577-A1 Novel peptide-forming enzyme gene AJINOMOTO CO., INC. (JP) 2004-10-14 — — US disclosed
CN-1529712-A Process for producing dipeptide, peptide-producing enzyme used therein, and process for producing peptide-producing enzyme ֮����ʽ���� 2004-09-15 — — CN disclosed
US-20040137558-A1 Process for producing dipeptide, peptide synthase to be used therein and process for producing peptide synthase AJINOMOTO CO., INC. (JP) 2004-07-15 — — US disclosed
EP-1411062-A1 PROCESS FOR PRODUCING DIPEPTIDE,PEPTIDE SYNTHASE TO BE USED THEREIN AND PROCESS FOR PRODUCING PEPTIDE SYNTHASE Ajinomoto Co., Inc. (JP) 2004-04-21 — — EP disclosed
EP-1411116-A1 PEPTIDE SYNTHASE GENE, PEPTIDE SYNTHASE AND PROCESS FOR PRODUCING DIPEPTIDE Ajinomoto Co., Inc. (JP) 2004-04-21 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230046772-A1 CX3CR1-BINDING POLYPEPTIDES COMPRISING IMMUNOGLOBULIN SINGLE VARIABLE DOMAINS CX3CR1, CCR5, CXCR3 NPY4R 1751/4885NPY1R 962/4885NPY5R 1850/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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