SCHEMBL24172000

SCHEMBL24172000

CCCCCCCCCCCCCOP(=O)(NCCN1CCCCC1)OCCCCCCCCCCCCC

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.45
LTA4H P09960 1/20 0.44
THRB P10828 4/20 0.41
THRA P10827 2/20 0.41
ALDH1A1 P00352 4/20 0.41
LPAR3 Q9UBY5 3/20 0.40
LPAR1 Q92633 2/20 0.40
LPAR2 Q9HBW0 2/20 0.40
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA9 Q16790 2/20 0.38
HRH3 Q9Y5N1 3/20 0.36
CARM1 Q86X55 1/20 0.36
PRMT6 Q96LA8 1/20 0.36
PRMT8 Q9NR22 1/20 0.36
LMNA P02545 2/20 0.36
CYP1A2 P05177 1/20 0.36
CHRM2 P08172 1/20 0.36
CHRM4 P08173 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24172002 0.91 LTA4H (0.44) KDM4ELTA4HTHRBTHRAALDH1A1
SCHEMBL24172009 0.86 TDP1 (0.44) THRBTHRAALDH1A1LPAR3LPAR1
SCHEMBL24172354 0.84 GAA (0.44) KDM4ETHRBTHRAALDH1A1LPAR3
SCHEMBL24172353 0.84 GAA (0.44) KDM4ETHRBTHRAALDH1A1LPAR3
SCHEMBL24172011 0.83 THRB (0.47) KDM4ETHRBALDH1A1LPAR3LPAR1
SCHEMBL24172593 0.83 KDM4E (0.41) KDM4ELTA4HTHRBTHRAALDH1A1
SCHEMBL24172012 0.83 KDM4E (0.41) KDM4ELTA4HTHRBTHRAALDH1A1
SCHEMBL24172005 0.81 KDM4E (0.39) KDM4ELTA4HTHRBTHRAALDH1A1
SCHEMBL24172016 0.77 KDM4E (0.38) KDM4ELTA4HTHRBTHRAALDH1A1
SCHEMBL24172584 0.77 KDM4E (0.38) KDM4ELTA4HTHRBTHRAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022002040-A1 LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS Suzhou Abogen Biosciences Co., Ltd. (CN) 2022-01-06 WO disclosed