Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 13/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24172000 | 0.83 | KDM4E (0.45) | THRBKDM4EALDH1A1LPAR3LPAR1 | |
| SCHEMBL24172009 | 0.81 | TDP1 (0.44) | THRBUSP2ALDH1A1LPAR3LPAR1 | |
| SCHEMBL24172002 | 0.78 | LTA4H (0.44) | THRBUSP2KDM4EALDH1A1LPAR3 | |
| SCHEMBL14041532 | 0.76 | THRB (0.45) | THRBKDM4ECYP2C19 | |
| SCHEMBL24172683 | 0.74 | TLR2 (0.41) | ALDH1A1LPAR3LPAR1LPAR2 | |
| SCHEMBL19865695 | 0.74 | GNAI3 (0.53) | THRB | |
| SCHEMBL4902299 | 0.74 | GNAI3 (0.53) | THRB | |
| SCHEMBL27553097 | 0.74 | GNAI3 (0.53) | THRB | |
| SCHEMBL19710765 | 0.74 | GNAI3 (0.53) | THRB | |
| SCHEMBL24172353 | 0.74 | GAA (0.44) | THRBKDM4EALDH1A1LPAR3LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022002040-A1 | LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS | Suzhou Abogen Biosciences Co., Ltd. (CN) | 2022-01-06 | — | — | WO | disclosed |