Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 2/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.37 |
| ▸ | AKT1 | P31749 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 3/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24172018 | 0.75 | LPAR3 (0.41) | CDC25ALPAR3LPAR1LPAR2AKT1 | |
| SCHEMBL24172001 | 0.74 | CDC25A (0.38) | CDC25ALPAR3LPAR1LPAR2AKT1 | |
| SCHEMBL5582947 | 0.69 | CDC25A (0.48) | CDC25ALPAR3LPAR1LPAR2AKT1 | |
| SCHEMBL8467492 | 0.69 | CYP3A4 (0.48) | CDC25ALPAR3LPAR1LPAR2AKT1 | |
| SCHEMBL19981530 | 0.68 | SMN1; SMN2 (0.38) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL22388964 | 0.68 | MEN1 (0.34) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL20926990 | 0.67 | MAPK1 (0.45) | ALDH1A1LMNASMN1; SMN2KCNH2 | |
| SCHEMBL11927923 | 0.67 | GNAI3 (0.56) | MEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL23344665 | 0.67 | MEN1 (0.32) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29389309 | 0.66 | KMT2A (0.58) | MEN1HTTKMT2AALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022002040-A1 | LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS | Suzhou Abogen Biosciences Co., Ltd. (CN) | 2022-01-06 | — | — | WO | disclosed |