Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.43 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 3/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8467492 | 0.97 | CYP3A4 (0.48) | CDC25ACYP3A4LPAR3LPAR2LPAR1 | |
| SCHEMBL5672809 | 0.90 | CDC25A (0.42) | CDC25ACYP3A4LPAR3LPAR2LPAR1 | |
| SCHEMBL8378718 | 0.89 | CDC25A (0.41) | CDC25ACYP3A4LPAR3LPAR2LPAR1 | |
| SCHEMBL8378588 | 0.84 | CDC25A (0.36) | CDC25ACYP3A4LMNAPOLBSMN1; SMN2 | |
| SCHEMBL2549102 | 0.83 | CYP3A4 (0.59) | CDC25ACYP3A4LPAR3LPAR2LPAR1 | |
| SCHEMBL3732273 | 0.83 | CDC25A (0.44) | CDC25ACYP3A4LPAR3LPAR2LPAR1 | |
| SCHEMBL5057044 | 0.82 | CDC25A (0.34) | CDC25ACYP3A4LMNAPOLBSMN1; SMN2 | |
| Pentane SCHEMBL29197938 | 0.75 | CYP3A4 (0.76) | CDC25ACYP3A4LPAR3LPAR2LPAR1 | |
| SCHEMBL11370402 | 0.75 | CYP3A4 (0.57) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL30540107 | 0.74 | LMNA (0.42) | CDC25ALMNAPOLBSMN1; SMN2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740189-B1 | LUNG SURFACTANT SUPPLEMENTS | CENTRE NAT RECH SCIENT (FR) | 2012-06-13 | — | — | EP | disclosed |
| EP-1740189-A1 | LUNG SURFACTANT SUPPLEMENTS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005099718-A1 | LUNG SURFACTANT SUPPLEMENTS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2005-10-27 | — | — | WO | disclosed |