Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.36 |
| ▸ | RXRA | P19793 | 6/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | CCR8 | P51685 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | F2RL3 | Q96RI0 | 3/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24048533 | 0.85 | ALOX5AP (0.36) | CYP3A4CCR1CCR5CCR8NOS3 | |
| SCHEMBL17248014 | 0.82 | NOS3 (0.42) | GAAGRIN1GRIN2BRXRACCR1 | |
| SCHEMBL11918256 | 0.81 | GAA (0.39) | GAAGRIN1GRIN2BRXRACYP3A4 | |
| SCHEMBL16044313 | 0.79 | GAA (0.35) | GAAGRIN1GRIN2BRXRACCR1 | |
| SCHEMBL15599228 | 0.79 | GAA (0.37) | GAAGRIN1GRIN2BRXRASCN9A | |
| SCHEMBL18371940 | 0.78 | LPAR1 (0.37) | GAAGRIN1GRIN2BRXRACYP3A4 | |
| SCHEMBL4150226 | 0.78 | PIK3CA (0.45) | CYP3A4CCR1CCR5CCR8NOS3 | |
| SCHEMBL22866537 | 0.77 | RXRA (0.34) | GAAGRIN1GRIN2BRXRATRPV4 | |
| SCHEMBL29560389 | 0.77 | RXRA (0.34) | GAAGRIN1GRIN2BRXRATRPV4 | |
| SCHEMBL25950819 | 0.77 | ALDH1A1 (0.34) | GAAGRIN1GRIN2BRXRAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022002097-A1 | PYRAZOLO[1,5-A]PYRIDINE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海艾力斯医药科技股份有限公司 | 2022-01-06 | — | — | WO | disclosed |