Agnuside

Agnuside

SCHEMBL24174405

O=C(OCC1=C[C@@H](O)[C@@H]2C=CO[C@@H](O[C@@H]3OC(CO)[C@@H](O)C(O)C3O)[C@H]12)c1ccc(O)cc1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.67
▸ HSP90AA1 P07900 9/20 0.56
▸ XDH P47989 1/20 0.44
▸ TYR P14679 1/20 0.41
▸ CA12 O43570 1/20 0.40
▸ CA1 P00915 1/20 0.40
▸ CA2 P00918 1/20 0.40
▸ CA9 Q16790 1/20 0.40
▸ CA14 Q9ULX7 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Agnuside SCHEMBL382107 1.00 L3MBTL1 (0.67) L3MBTL1HSP90AA1XDHTYRCA12
Agnuside SCHEMBL13208121 1.00 L3MBTL1 (0.67) L3MBTL1HSP90AA1XDHTYRCA12
SCHEMBL7153129 0.93 L3MBTL1 (0.67) L3MBTL1HSP90AA1XDHCA12CA1
Eurostoside SCHEMBL29425819 0.85 L3MBTL1 (0.62) L3MBTL1HSP90AA1XDHCA12CA1
SCHEMBL29425816 0.83 L3MBTL1 (0.63) L3MBTL1HSP90AA1XDHTYR
Aucubin SCHEMBL381032 0.81 L3MBTL1 (1.00) L3MBTL1HSP90AA1XDH
Aucubin SCHEMBL22680275 0.81 L3MBTL1 (1.00) L3MBTL1HSP90AA1XDH
Aucubin SCHEMBL22680274 0.81 L3MBTL1 (1.00) L3MBTL1HSP90AA1XDH
SCHEMBL13998199 0.78 KMT2A (0.42) L3MBTL1HSP90AA1CA12CA1CA2
SCHEMBL382085 0.77 STAT3 (0.44) L3MBTL1HSP90AA1TYRCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11364255-B2 Therapeutic herbal compositions for improving joint health KARALLIEF, INC. (US) 2022-06-21 — — US disclosed
US-20220000898-A1 THERAPEUTIC HERBAL COMPOSITIONS FOR IMPROVING JOINT HEALTH Karallief Inc. 2022-01-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220000898-A1 THERAPEUTIC HERBAL COMPOSITIONS FOR IMPROVING JOINT HEALTH RDX, HAGH, BROX L3MBTL1 3535/4885HSP90AA1 164/4885XDH 3485/4885
US-11364255-B2 Therapeutic herbal compositions for improving joint health RDX, HAGH, BROX L3MBTL1 3535/4885HSP90AA1 164/4885XDH 3485/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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