Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.47 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PAK4 | O96013 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21405827 | 0.89 | STING1 (0.45) | CSNK2A2CSNK2BCSNK2A1KDRALDH1A1 | |
| SCHEMBL21405985 | 0.86 | ALDH1A1 (0.39) | CSNK2A2CSNK2BCSNK2A1KDRALDH1A1 | |
| SCHEMBL30416042 | 0.86 | ALDH1A1 (0.39) | CSNK2A2CSNK2BCSNK2A1KDRALDH1A1 | |
| SCHEMBL21406148 | 0.82 | STING1 (0.52) | ALDH1A1KDM4ESTING1MAPTGAA | |
| SCHEMBL24175695 | 0.80 | STING1 (0.53) | KDM4ESTING1 | |
| SCHEMBL21405800 | 0.80 | STING1 (0.44) | CSNK2A2CSNK2BCSNK2A1KDRKDM4E | |
| SCHEMBL30416428 | 0.80 | STING1 (0.44) | CSNK2A2CSNK2BCSNK2A1KDRKDM4E | |
| SCHEMBL21454853 | 0.79 | STING1 (0.52) | ALDH1A1KDM4EHPGDSTING1NPC1 | |
| SCHEMBL24175168 | 0.78 | STING1 (0.65) | CSNK2A2CSNK2BCSNK2A1KDRALDH1A1 | |
| SCHEMBL21436929 | 0.78 | STING1 (0.44) | ALDH1A1KDM4EHPGDSTING1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022002077-A1 | ARYL AROMATIC HETEROCYCLIC DERIVATIVE AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海海和药物研究开发股份有限公司 | 2022-01-06 | — | — | WO | disclosed |