Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 2/20 | 0.34 |
| ▸ | BRAF | P15056 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4882490 | 0.83 | TSHR (0.49) | KMT2AMEN1TSHRALDH1A1CYP1A2 | |
| SCHEMBL4881920 | 0.83 | TP53 (0.47) | ENPP2KMT2AMEN1TSHRMAPT | |
| SCHEMBL24176322 | 0.83 | ENPP2 (0.49) | ENPP2KMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL13858451 | 0.75 | ALDH1A1 (0.42) | KMT2AMEN1ALDH1A1HSD17B10SRC | |
| SCHEMBL24176474 | 0.74 | PDE2A (0.47) | ENPP2LMNA | |
| SCHEMBL12335147 | 0.63 | SMN1; SMN2 (0.46) | KMT2AMEN1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL1073710 | 0.60 | BRAF (0.43) | ALDH1A1MAPTPOLBSRCBRAF | |
| SCHEMBL1094177 | 0.60 | PTGS2 (0.47) | TSHRALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL6086540 | 0.59 | NPC1 (0.43) | KMT2AMEN1TSHRALDH1A1CYP1A2 | |
| SCHEMBL13860846 | 0.58 | NTRK1 (0.38) | TSHRALDH1A1HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022003377-A1 | THIENO[3,4-C]PYRAZOL-3-YL ACETAMIDES AS AUTOTAXIN INHIBITORS | UNI-PHARMA KLEON TSETIS PHARMACEUTICAL LABORATORIES S.A. (GR) | 2022-01-06 | — | — | WO | disclosed |