Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALAD | P13716 | 2/20 | 0.72 |
| ▸ | IKBKB | O14920 | 3/20 | 0.53 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.39 |
| ▸ | SELE | P16581 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2652069 | 0.84 | ALAD (1.00) | ALADMEN1KMT2AHDAC6CNR1 | |
| SCHEMBL15177354 | 0.82 | ALAD (0.72) | ALADHDAC6CNR1IKBKEAURKB | |
| SCHEMBL5605556 | 0.81 | HDAC6 (0.62) | ALADIKBKBMEN1KMT2AHDAC6 | |
| SCHEMBL3196052 | 0.81 | ALAD (0.56) | ALADHDAC6MKNK1MKNK2MMP12 | |
| SCHEMBL5605301 | 0.80 | MMP12 (0.52) | ALADIKBKBMAP4K4HDAC6CASP1 | |
| SCHEMBL8342325 | 0.79 | ALAD (0.46) | ALADHDAC6CDK2IKBKEAURKB | |
| SCHEMBL6141881 | 0.79 | MMP12 (0.48) | ALADHDAC6CDK2IKBKEAURKB | |
| SCHEMBL21563725 | 0.78 | ALAD (0.66) | ALADMEN1KMT2AHDAC6CNR1 | |
| SCHEMBL13267656 | 0.78 | ALAD (0.66) | ALADIKBKBHDAC6CNR1MAPT | |
| SCHEMBL6704697 | 0.78 | ALAD (0.71) | ALADCNR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220002796-A1 | QUALITY CONTROL OF LNA OLIGONUCLEOTIDE THERAPEUTICS USING MASSIVELY PARALLEL SEQUENCING | ROCHE INNOVATION CENTER COPENHAGEN A/S (DK) | 2022-01-06 | — | — | US | disclosed |