⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26935813 | 0.93 | CACNA2D1 (0.31) | — | |
| SCHEMBL24176504 | 0.91 | KMT2A (0.31) | — | |
| SCHEMBL26935872 | 0.90 | KMT2A (0.31) | — | |
| SCHEMBL26935817 | 0.88 | — | — | |
| SCHEMBL26935816 | 0.84 | CYP1A2 (0.31) | — | |
| SCHEMBL12786202 | 0.84 | L3MBTL1 (0.35) | — | |
| SCHEMBL2858384 | 0.84 | L3MBTL1 (0.35) | — | |
| SCHEMBL4841739 | 0.84 | L3MBTL1 (0.35) | — | |
| SCHEMBL31642941 | 0.84 | L3MBTL1 (0.35) | — | |
| SCHEMBL31043202 | 0.84 | L3MBTL1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11840550-B2 | Silyl-biaryl phosphoramidites and methods of making | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-12-12 | — | — | US | disclosed |
| US-11840550-B2 | Silyl-biaryl phosphoramidites and methods of making | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-12-12 | — | — | US | disclosed |
| US-20220002328-A1 | SILYL-BIARYL PHOSPHORAMIDITES AND METHODS OF MAKING | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2022-01-06 | — | — | US | disclosed |